Journal
FRONTIERS OF MATERIALS SCIENCE
Volume 8, Issue 1, Pages 46-52Publisher
HIGHER EDUCATION PRESS
DOI: 10.1007/s11706-014-0231-2
Keywords
aerogel; sol-gel technique; bioactive material; SAOS-2 cell
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Funding
- European Union
- European Social Fund
- [TAMOP-4.2.2.A-11/1/KONV-2012-0036]
- [OTKA76834]
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In this study, the possibility of preparation and application of highly porous silica aerogel-based bioactive materials are presented. The aerogel was combined with hydroxyapatite and beta-tricalcium phosphate as bioactive and osteoinductive agents. The porosity of aerogels was in the mesoporous region with a maximum pore diameter of 7.4 and 12.7 nm for the composite materials. The newly developed bioactive materials were characterized by scanning electron microscopy. The in vitro biological effect of these modified surfaces was also tested on SAOS-2 osteogenic sarcoma cells by confocal laser scanning microscopy.
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