4.1 Article

Treatment of Complicated Urinary Tract Infections With an Emphasis on Drug-Resistant Gram-Negative Uropathogens

Journal

CURRENT INFECTIOUS DISEASE REPORTS
Volume 15, Issue 2, Pages 109-115

Publisher

SPRINGER
DOI: 10.1007/s11908-013-0315-7

Keywords

Complicated; Urinary tract; Infection; Drug resistance; Gram-negative bacilli; Uropathogens; Trimethoprim/sulfamethoxazole; Fluoroquinolones; Nitrofurantoin; Fosfomycin; Amoxicillin/clavulanic acid; Third-generation cephalosporins; Aztreonam; Beta-lactam/beta-lactamase inhibitor combinations; Cefepime; Carbapenems; ESBL; AmpC beta-lactamase; Carbapenemase; Treatment guidelines

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Complicated urinary tract infection is a challenging infection, since cure is difficult and either persistence or recurrence is common. The challenge is frequently increased because complicated urinary tract infection is often caused by gram-negative bacilli resistant to multiple antimicrobial drugs. In this review, we approach the therapy of complicated urinary tract infection with an emphasis on those caused by antimicrobial drug-resistant gram-negative uropathogens.

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