Journal
CURRENT INFECTIOUS DISEASE REPORTS
Volume 14, Issue 3, Pages 213-226Publisher
SPRINGER
DOI: 10.1007/s11908-012-0252-x
Keywords
NDM-1; Antimicrobial resistance; Carbapenemase; Metallo-beta-lactamases; Medical tourism; Antibiotic resistance; ESBL (extended spectrum beta-lactamases); Beta-lactamases; New Delhi beta-lactamase; Multidrug resistance; Carbapenems; CTX; Gram-negatives; Resistome; Lateral genetic transfer; Mobile genetic elements; bla(NDM-1)
Categories
Funding
- International Society of Travel Medicine
- JWID
- Up-To-Date
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Antimicrobial resistance is a growing problem globally. The appearance and spread of bacteria that are resistant to most or all commonly available antibiotics has raised the specter of untreatable bacterial infections. The New Delhi metallo-beta-lactamase-1 (NDM-1) has received wide attention because of the extreme resistance it confers, its presence in many common pathogens, its rapid spread to multiple continents, and local nosocomial spread in some areas. Most early reports of infections were in individuals who had received medical care in the Indian subcontinent. This paper will explore the role of travelers in the movement of pathogens and microbial genetic material associated with resistance, with a special focus on the appearance and dispersal of bacteria carrying this mobile genetic element, bla(NDM-1), and the contributing factors, including growing long-distance travel and expansion of travel across international borders for medical, dental, and surgical care (medical tourism).
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