4.1 Article

Viral Infections of the Lower Respiratory Tract

Journal

CURRENT INFECTIOUS DISEASE REPORTS
Volume 14, Issue 3, Pages 284-291

Publisher

SPRINGER
DOI: 10.1007/s11908-012-0258-4

Keywords

Lower respiratory tract infection; Pneumonia; Bronchiolitis; Bronchitis; Symptoms; Clinical characteristics; Respiratory virus; Human metapneumovirus; Human coronavirus; Rhinovirus; Bocavirus; WU polyomavirus; KI polyomavirus; Parechovirus; Pathogenicity; Epidemiology; Seroprevalence; Seasonal distribution; Incidence; Percentage; Genotype; Coinfection; Age; Children; Adult

Funding

  1. National Major S&T Research Projects for the Control and Prevention of Major Infectious Diseases in China [2009ZX10004-206]
  2. Fondation Merieux

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Lower respiratory tract infections (LRTIs) are a global burden to public health and are frequently caused by respiratory viruses. Advances in molecular diagnostic techniques have allowed the identification of previously undetected viral pathogens and have improved our understanding of respiratory virus infections. Here we review the epidemiological and clinical characteristics of recently identified viruses including human metapneumovirus, human coronaviruses NL63 and HKU1, human rhinovirus C, bocavirus, WU and KI polyomaviruses, and parechovirus. The roles of these viruses in LRTIs in children and adults are discussed.

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