4.5 Article

Electrochemical- and Fluorescent-Mediated Signal Amplifications for Rapid Detection of Low-Abundance Circulating Tumor Cells on a Paper-Based Microfluidic Immunodevice

Journal

CHEMELECTROCHEM
Volume 1, Issue 4, Pages 722-727

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/celc.201300194

Keywords

circulating tumor cells; electrochemical immunodevices; electrochemistry; fluorescence; microfluidics

Funding

  1. Nanyang Technological University College of Engineering
  2. Ministry of Education of Singapore [RG 26/11]
  3. SingHealth Foundation
  4. Singapore National Medical Research Council

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The design of a novel paper-based microfluidic immunodevice with combined electrochemical- and fluorescent-mediated signal amplifications for the highly specific and ultrasensitive point-of-care detection of rare circulating tumor cells is reported.

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