Hybrid C3N4/Fluorine-Doped Tin Oxide Electrode Transfers Hydride for 1,4-NADH Cofactor Regeneration

Herein, we report the use of graphitic carbon nitride (C3N4)-modified fluorine-doped tin oxide electrodes for the electroregeneration of reduced nicotinamide adenine dinucleotide phosphate (NADH). We synthesized and functionalized these hybrid electrodes by using anodic aluminum-oxide-templated C3N4 growth. Electrochemical activation of the semiconducting C3N4 islands with a rhodium complex permits selective regeneration of biologically active 1,4-NADH cofactor.