Related references
Note: Only part of the references are listed.Review of high-dose intravenous vitamin C as an anticancer agent
Michelle K. Wilson et al.
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2014)
Intracellular ascorbate enhances hypoxia-inducible factor (HIF)-hydroxylase activity and preferentially suppresses the HIF-1 transcriptional response
Caroline Kuiper et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Increased tumor ascorbate is associated with extended disease-free survival and decreased hypoxia-inducible factor-1 activation in human colorectal cancer
Caroline Kuiper et al.
FRONTIERS IN ONCOLOGY (2014)
Human skeletal muscle ascorbate is highly responsive to changes in vitamin C intake and plasma concentrations
Anitra C. Carr et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2013)
Ascorbate Induces Ten-Eleven Translocation (Tet) Methylcytosine Dioxygenase-mediated Generation of 5-Hydroxymethylcytosine
Emily A. Minor et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
Gregg L. Semenza
JOURNAL OF CLINICAL INVESTIGATION (2013)
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
Peter J. Ratcliffe
JOURNAL OF PHYSIOLOGY-LONDON (2013)
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
Gregg L. Semenza
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Dietary ascorbate intake affects steady state tissue concentrations in vitamin C-deficient mice: tissue deficiency after suboptimal intake and superior bioavailability from a food source (kiwifruit)
Margreet C. M. Vissers et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2011)
Vitamin C is dispensable for oxygen sensing in vivo
Katarzyna J. Nytko et al.
BLOOD (2011)
Redox-modulatory vitamins and minerals that prospectively predict mortality in older British people: the National Diet and Nutrition Survey of people aged 65 years and over
Christopher J. Bates et al.
BRITISH JOURNAL OF NUTRITION (2011)
The SLC23 family of ascorbate transporters: ensuring that you get and keep your daily dose of vitamin C
James M. May
BRITISH JOURNAL OF PHARMACOLOGY (2011)
HIF1A Overexpression Is Associated with Poor Prognosis in a Cohort of 731 Colorectal Cancers
Yoshifumi Baba et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents
Emily Flashman et al.
BIOCHEMICAL JOURNAL (2010)
Guidelines for the welfare and use of animals in cancer research
P. Workman et al.
BRITISH JOURNAL OF CANCER (2010)
Low Ascorbate Levels Are Associated with Increased Hypoxia-Inducible Factor-1 Activity and an Aggressive Tumor Phenotype in Endometrial Cancer
Caroline Kuiper et al.
CANCER RESEARCH (2010)
Serum vitamin C and the prevalence of vitamin C deficiency in the United States: 2003-2004 National Health and Nutrition Examination Survey (NHANES)
Rosemary L. Schleicher et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2009)
Vitamin C: update on physiology and pharmacology
J. Mandl et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Vitamin C Requirements in Parenteral Nutrition
Mette M. Berger
GASTROENTEROLOGY (2009)
Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets
Johanna Myllyharju
ANNALS OF MEDICINE (2008)
Estimated prevalence and predictors of vitamin C deficiency within UK's low-income population
Annhild Mosdol et al.
JOURNAL OF PUBLIC HEALTH (2008)
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice
Qi Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Hypoxia and cancer
M. Christiane Brahimi-Horn et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2007)
HIF-dependent antitumorigenic effect of antioxidants in vivo
Ping Gao et al.
CANCER CELL (2007)
The role of ascorbate in the modulation of HIF-1α protein and HIF-dependent transcription by chromium(VI) and nickel(II)
Monika Kaczmarek et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Modulation of hypoxia-inducible factor-1 alpha in cultured primary cells by intracellular ascorbate
Margret C. M. Vissers et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Depletion of ascorbic acid restricts angiogenesis and retards tumor growth in a mouse model
Sucheta Telang et al.
NEOPLASIA (2007)
Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one?
Abdullah Ozer et al.
NATURE CHEMICAL BIOLOGY (2007)
Cancer's molecular sweet tooth and the Warburg effect
Jung-whan Kim et al.
CANCER RESEARCH (2006)
Enhanced response to radiotherapy in tumours deficient in the function of hypoxia-inducible factor-1
KJ Williams et al.
RADIOTHERAPY AND ONCOLOGY (2005)
Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases
P Koivunen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
D Lando et al.
GENES & DEVELOPMENT (2002)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)
Aortic wall damage in mice unable to synthesize ascorbic acid
N Maeda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)