Related references
Note: Only part of the references are listed.DNMT3A mutations at R882 hotspot are only found in major clones of acute myeloid leukemia
Kathrin E. Bisling et al.
LEUKEMIA & LYMPHOMA (2014)
Phospho Switch Triggers Brd4 Chromatin Binding and Activator Recruitment for Gene-Specific Targeting
Shwu-Yuan Wu et al.
MOLECULAR CELL (2013)
Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
Panagis Filippakopoulos et al.
CELL (2012)
Low frequency of DNMT3A mutations in pediatric AML, and the identification of the OCI-AML3 cell line as an in vitro model
I. H. I. M. Hollink et al.
LEUKEMIA (2012)
Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia
E. McCormack et al.
LEUKEMIA (2012)
The NPM1 wild-type OCI-AML2 and the NPM1-mutated OCI-AML3 cell lines carry DNMT3A mutations
E. Tiacci et al.
LEUKEMIA (2012)
BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
Jake E. Delmore et al.
CELL (2011)
Histone deacetylase inhibitors augment doxorubicin-induced DNA damage in cardiomyocytes
Katherine Ververis et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2011)
A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes
Jagat C. Borah et al.
CHEMISTRY & BIOLOGY (2011)
The polo-like kinase inhibitor BI 2536 exhibits potent activity against malignant plasma cells and represents a novel therapy in multiple myeloma
Helen J. Stewart et al.
EXPERIMENTAL HEMATOLOGY (2011)
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
Johannes Zuber et al.
NATURE (2011)
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
Mark A. Dawson et al.
NATURE (2011)
Targeting MYC dependence in cancer by inhibiting BET bromodomains
Jennifer A. Mertz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The impact of acetylation and deacetylation on the p53 pathway
Christopher L. Brooks et al.
PROTEIN & CELL (2011)
New insights into p53 activation
Christopher L. Brooks et al.
CELL RESEARCH (2010)
Suppression of inflammation by a synthetic histone mimic
Edwige Nicodeme et al.
NATURE (2010)
BRD7 is a candidate tumour suppressor gene required for p53 function
Jarno Drost et al.
NATURE CELL BIOLOGY (2010)
A minority of foci or pan-nuclear apoptotic staining of γH2AX in the S phase after UV damage contain DNA double-strand breaks
Sebastien de Feraudy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes
Terry J. Gaymes et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2009)
Brd4 Coactivates Transcriptional Activation of NF-κB via Specific Binding to Acetylated RelA
Bo Huang et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
H2AX Is Required for Cell Cycle Arrest via the p53/p21 Pathway
Michalis Fragkos et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Acetylation is indispensable for p53 activation
Yi Tang et al.
CELL (2008)
Chromatin modifications and their function
Tony Kouzarides
CELL (2007)
DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells
Bipasha Mukherjee et al.
DNA REPAIR (2006)
p53-dependent transcriptional repression of c-myc is required for G(1) cell cycle arrest
JSL Ho et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
LT Vassilev et al.
SCIENCE (2004)
Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation
CL Brooks et al.
CURRENT OPINION IN CELL BIOLOGY (2003)
DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53
RA Woo et al.
EMBO JOURNAL (2002)
Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases
NA Barlev et al.
MOLECULAR CELL (2001)
p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2
A Ito et al.
EMBO JOURNAL (2001)
The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest
S Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)