Journal
BONE & JOINT RESEARCH
Volume 3, Issue 6, Pages 193-202Publisher
BRITISH EDITORIAL SOC BONE JOINT SURGERY
DOI: 10.1302/2046-3758.36.2000281
Keywords
Tendon; Tendinopathy; Animal Model; Literature Review
Categories
Funding
- DJO
- Amniox
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Tendinopathy is a debilitating musculoskeletal condition which can cause significant pain and lead to complete rupture of the tendon, which often requires surgical repair. Due in part to the large spectrum of tendon pathologies, these disorders continue to be a clinical challenge. Animal models are often used in this field of research as they offer an attractive framework to examine the cascade of processes that occur throughout both tendon pathology and repair. This review discusses the structural, mechanical, and biological changes that occur throughout tendon pathology in animal models, as well as strategies for the improvement of tendon healing.
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