Related references
Note: Only part of the references are listed.Insulin glargine and receptor-mediated signalling: Clinical implications in treating type 2 diabetes
Derek Le Roith
DIABETES-METABOLISM RESEARCH AND REVIEWS (2007)
Role of c-Abl in directing metabolic versus mitogenic effects in insulin receptor signaling
Francesco Frasca et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Serum C-peptide, IGFBP-1 and IGFBP-2 and risk of colon and rectal cancers in the European Prospective Investigation into Cancer and Nutrition
Mazda Jenab et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Functional responses and in vivo anti-tumour activity of h7C10: A humanised monoclonal antibody with neutralising activity against the insulin-like growth factor-1 (IGF-1) receptor and insulin/IGF-1 hybrid receptors
Giuseppe Pandini et al.
EUROPEAN JOURNAL OF CANCER (2007)
Implication of the insulin-like growth factor-IR pathway in the resistance of non-small cell lung cancer cells totreatment with gefitinib
Floriana Morgillo et al.
CLINICAL CANCER RESEARCH (2007)
被撤回的出版物: High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2 (Retracted article. See vol. 123, pg. 4979, 2013)
Giovanna Maria Pierantoni et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
被撤回的出版物: High Mobility Group A1 (HMGA1) proteins interact with p53 and inhibit its apoptotic activity (Retracted article. See vol. 21, pg. 503, 2014)
G. M. Pierantoni et al.
CELL DEATH AND DIFFERENTIATION (2006)
Insulin-like growth factor-1 increases bone sialoprotein (BSP) expression through fibroblast growth factor-2 response element and homeodomain protein-binding site in the proximal promoter of the BSP gene
Youhei Nakayama et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
Role of insulin receptor in the regulation of glucose uptake in neonatal hepatocytes
Carmen Nevado et al.
ENDOCRINOLOGY (2006)
HMGA1 inhibits the function of p53 family members in thyroid cancer cells
F Frasca et al.
CANCER RESEARCH (2006)
The insulin-like growth factor receptor 1 is a promising target for novel treatment approaches in neuroendocrine gastrointestinal tumours
M Höpfner et al.
ENDOCRINE-RELATED CANCER (2006)
Increased cancer-related mortality for patients with type 2 diabetes who use sulforrylureas or insulin
SL Bowker et al.
DIABETES CARE (2006)
Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: A supporting role to the epidermal growth factor receptor
JM Knowlden et al.
ENDOCRINOLOGY (2005)
Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy
TH Ho et al.
JOURNAL OF CELL SCIENCE (2005)
Metformin and reduced risk of cancer in diabetic patients
JMM Evans et al.
BMJ-BRITISH MEDICAL JOURNAL (2005)
Insulin-like growth factor-I receptor activity is essential for Kaposi's sarcoma growth and survival
SB Catrina et al.
BRITISH JOURNAL OF CANCER (2005)
Molecular and genetic studies imply Akt-mediated signaling promotes protein kinase CβII alternative splicing via phosphorylation of serine/arginine-rich splicing factor SRp40
NA Patel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome
T Apridonidze et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
MBNL1 is the primary determinant of focus formation and aberrant insulin receptor splicing in DM1
W Dansithong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
DD Sarbassov et al.
SCIENCE (2005)
The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy
GS Warshamana-Greene et al.
CLINICAL CANCER RESEARCH (2005)
Differential gene expression of insulin receptor isoforms A and B and insulin receptor substrates 1, 2 and 3 in rat tissues:: modulation by aging and differentiation in rat adipose tissue
R Serrano et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2005)
Restraining PI3K: mTOR signalling goes back to the membrane
LS Harrington et al.
TRENDS IN BIOCHEMICAL SCIENCES (2005)
Inhibition of insulin-like growth factor-1 receptor signaling enhances growth-inhibitory and proapoptotic effects of gefitinib (Iressa) in human breast cancer cells
A Camirand et al.
BREAST CANCER RESEARCH (2005)
Insulin-like growth factor I controls adhesion strength mediated by alpha(5)beta(1) integrins in motile carcinoma cells
L Lynch et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
HIV-1 accessory protein Vpr inhibits the effect of insulin on the Foxo subfamily of forkhead transcription factors by interfering with their binding to 14-3-3 proteins - Potential clinical implications regarding the insulin resistance of HIV-1-infected patients
T Kino et al.
DIABETES (2005)
CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing
AN Ladd et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A prospective study of plasma C-peptide and colorectal cancer risk in men
J Ma et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2004)
Insulin regulates protein kinase CβII alternative splicing in multiple target tissues:: Development of a hormonally responsive heterologous minigene
NA Patel et al.
MOLECULAR ENDOCRINOLOGY (2004)
PDK1, the master regulator of AGC kinase signal transduction
A Mora et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2004)
Prediagnostic levels of C-peptide, IGF-I, IGFBP-1,-2 and-3
A Lukanova et al.
INTERNATIONAL JOURNAL OF CANCER (2004)
Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer
R Sgarra et al.
FEBS LETTERS (2004)
Muscleblind proteins regulate alternative splicing
TH Ho et al.
EMBO JOURNAL (2004)
Overweight, obesity and cancer: Epidemiological evidence and proposed mechanisms
EE Calle et al.
NATURE REVIEWS CANCER (2004)
Relative amounts of antagonistic splicing factors, hnRNP A1 and ASF/SF2, change during neoplastic lung growth: Implications for pre-mRNA processing
LK Zerbe et al.
MOLECULAR CARCINOGENESIS (2004)
Assembly of splicing complexes on exon 11 of the human insulin receptor gene does not correlate with splicing efficiency in-vitro
NJG Webster et al.
BMC MOLECULAR BIOLOGY (2004)
Insulin-like growth factors and neoplasia
MN Pollak et al.
NATURE REVIEWS CANCER (2004)
Insulin-like growth factor-1 receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells
HE Jones et al.
ENDOCRINE-RELATED CANCER (2004)
Control of cell size through phosphorylation of upstream binding factor 1 by nuclear phosphatidylinositol 3-kinase
R Drakas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults
SS Coughlin et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2004)
Insulin receptor splicing alteration in myotonic dystrophy type 2
RS Savkur et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Insulin stimulation of GLUT4 exocytosis, but not its inhibition of endocytosis, is dependent on RabGAP AS160
A Zeigerer et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Isoform-specific insulin receptor signaling involves different plasma membrane domains
S Uhles et al.
JOURNAL OF CELL BIOLOGY (2003)
Specificity of insulin-like growth factor I and insulin on Shc phosphorylation and Grb2 recruitment in caveolae
C Biedi et al.
ENDOCRINOLOGY (2003)
Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor
JJ Hu et al.
MOLECULAR CELL (2003)
The insulin-like growth factor system and cancer
D LeRoith et al.
CANCER LETTERS (2003)
Signaling differences from the A and B isoforms of the insulin receptor (IR) in 32D cells in the presence or absence of IR substrate-1
L Sciacca et al.
ENDOCRINOLOGY (2003)
Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation
H Sano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults
EE Calle et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
A nucleoprotein complex containing sp1, C/EBPβ, and HMGI-Y controls human insulin receptor gene transcription
D Foti et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A
L Sciacca et al.
ONCOGENE (2002)
Microarray analysis of insulin and insulin-like growth factor-1 (IGF-1) receptor signaling reveals the selective up-regulation of the mitogen heparin-binding EGF-like growth factor by IGF-1
C Mulligan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved
G Pandini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Functional insulin receptors on human epithelial ovarian carcinoma cells: Implications for IGF-II mitogenic signaling
KR Kalli et al.
ENDOCRINOLOGY (2002)
Cell cycle and death control: long live Forkheads
BMT Burgering et al.
TRENDS IN BIOCHEMICAL SCIENCES (2002)
APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes
J Liu et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K
SC Kozma et al.
BIOESSAYS (2002)
Alanine scanning mutagenesis of a type 1 insulin-like growth factor receptor ligand binding site
J Whittaker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Molecular biology of HMGA proteins: hubs of nuclear function
R Reeves
GENE (2001)
A PDZ domain protein interacts with the C-terminal tail of the insulin-like growth factor-1 receptor but not with the insulin receptor
T Ligensa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy
RS Savkur et al.
NATURE GENETICS (2001)
Insulin regulates alternative splicing of protein kinase C βII through a phosphatidylinositol 3-kinase-dependent pathway involving the nuclear serine/arginine-rich splicing factor, SRp40, in skeletal muscle cells
NA Patel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The IGF system in thyroid cancer: new concepts
V Vella et al.
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY (2001)
IGF-I receptor signalling in transformation and differentiation
B Valentinis et al.
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY (2001)
Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10
SH Chiang et al.
NATURE (2001)
Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic β cells
B Leibiger et al.
MOLECULAR CELL (2001)
An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control
W Brogiolo et al.
CURRENT BIOLOGY (2001)
Signal integration and the specificity of insulin action
M Kanzaki et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2001)
Mechanism of transmembrane signaling: Insulin binding and the insulin receptor
FP Ottensmeyer et al.
BIOCHEMISTRY (2000)
Role of the insulin-like growth factor family in cancer development and progression
H Yu et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2000)
CAP defines a second signalling pathway required for insulin-stimulated glucose transport
CA Baumann et al.
NATURE (2000)
The functional significance of Shc in insulin signaling as a substrate of the insulin receptor
T Sasaoka et al.
ENDOCRINE JOURNAL (2000)
The differential effects of pp120 (Ceacam 1) on the mitogenic action of insulin and insulin-like growth factor 1 are regulated by the nonconserved tyrosine 1316 in the insulin receptor
P Soni et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Function of the IGF-I receptor in breast cancer
E Surmacz
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2000)