Journal
AGING AND DISEASE
Volume 5, Issue 3, Pages 212-217Publisher
INT SOC AGING & DISEASE
DOI: 10.14336/AD.2014.0500212
Keywords
Aging; glycation; oxidative stress; reactive nitrogen species; reactive oxygen species
Categories
Ask authors/readers for more resources
Uncontrolled continued exposure to oxidative stress is a precursor to many chronic diseases including cancer, diabetes, degenerative disorders and cardiovascular diseases. Of the many known mediators of oxidative stress, reactive oxygen species (ROS) and advanced glycation end products (AGEs) are the most studied. In the present review, we have summarized current data on the origin of circulating AGEs, discussed issues associated with reliable assessment of its steady state level, and changes in its level with age and select metabolic diseases. Lastly, we have made recommendations about life style changes that may decrease AGEs burden to promote healthy aging.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available