Related references
Note: Only part of the references are listed.A whole brain longitudinal study in the YAC128 mouse model of Huntington's disease shows distinct trajectories of neurochemical, structural connectivity and volumetric changes
Lorena I. Petrella et al.
HUMAN MOLECULAR GENETICS (2018)
Brain-Derived Neurotrophic Factor Prevents Depressive-Like Behaviors in Early-Symptomatic YAC128 Huntington's Disease Mice
Victor Silva da Fonseca et al.
MOLECULAR NEUROBIOLOGY (2018)
Probucol attenuates lipopolysaccharide-induced leukocyte recruitment and inflammatory hyperalgesia: effect on NF-κB activation and cytokine production
Amanda Z. Zucoloto et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2017)
Treadmill exercise delays the onset of non-motor behaviors and striatal pathology in the CAG140 knock-in mouse model of Huntington's disease
D. P. Stefanko et al.
NEUROBIOLOGY OF DISEASE (2017)
Protective Effect of Antioxidants on Neuronal Dysfunction and Plasticity in Huntington's Disease
Thirunavukkarasu Velusamy et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)
Correlations of Behavioral Deficits with Brain Pathology Assessed through Longitudinal MRI and Histopathology in the HdhQ150/Q150 Mouse Model of Huntington's Disease
Ivan Rattray et al.
PLOS ONE (2017)
Probucol inhibits LPS-induced microglia activation and ameliorates brain ischemic injury in normal and hyperlipidemic mice
Yeon Suk Jung et al.
ACTA PHARMACOLOGICA SINICA (2016)
N-acetylcysteine modulates glutamatergic dysfunction and depressive behavior in Huntington's disease
Dean J. Wright et al.
HUMAN MOLECULAR GENETICS (2016)
Neuropsychiatric symptoms are very common in premanifest and early stage Huntington's Disease
Saul Martinez-Horta et al.
PARKINSONISM & RELATED DISORDERS (2016)
Time-Course Analysis of Protein and Lipid Oxidation in the Brains of Yac128 Huntington's Disease Transgenic Mice
Patricia S. Brocardo et al.
REJUVENATION RESEARCH (2016)
Longitudinal in vivo MRI in a Huntington's disease mouse model: Global atrophy in the absence of white matter microstructural damage
Jessica J. Steventon et al.
SCIENTIFIC REPORTS (2016)
Did we abandon probucol too soon?
Shizuya Yamashita et al.
CURRENT OPINION IN LIPIDOLOGY (2015)
The current state of the neurogenic theory of depression and anxiety
Bradley R. Miller et al.
CURRENT OPINION IN NEUROBIOLOGY (2015)
The influence of the HPG axis on stress response and depressive-like behaviour in a transgenic mouse model of Huntington's disease
X. Du et al.
EXPERIMENTAL NEUROLOGY (2015)
Probucol Protects Against Asymmetric Dimethylarginine-Induced Apoptosis in the Cultured Human Brain Microvascular Endothelial Cells
Jiwei Ma et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2015)
Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease
Amber L. Southwell et al.
NEUROBIOLOGY OF DISEASE (2015)
Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors
Alexis S. Hill et al.
NEUROPSYCHOPHARMACOLOGY (2015)
PROBUCOL MITIGATES STREPTOZOTOCIN-INDUCED COGNITIVE AND BIOCHEMICAL CHANGES IN MICE
D. B. Santos et al.
NEUROSCIENCE (2015)
Huntington disease
Gillian P. Bates et al.
NATURE REVIEWS DISEASE PRIMERS (2015)
YAC128 Huntington's disease transgenic mice show enhanced short-term hippocampal synaptic plasticity early in the course of the disease
Mohamed Ghilan et al.
BRAIN RESEARCH (2014)
IGF-1 Intranasal Administration Rescues Huntington's Disease Phenotypes in YAC128 Mice
Carla Lopes et al.
MOLECULAR NEUROBIOLOGY (2014)
Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects
Ian Mahar et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2014)
Effects of Deletion of Mutant Huntingtin in Steroidogenic Factor 1 Neurons on the Psychiatric and Metabolic Phenotype in the BACHD Mouse Model of Huntington Disease
Barbara Baldo et al.
PLOS ONE (2014)
Hypothalamic expression of mutant huntingtin contributes to the development of depressive-like behavior in the BAC transgenic mouse model of Huntingtons disease
Sofia Hult Lundh et al.
HUMAN MOLECULAR GENETICS (2013)
Differential effects of early environmental enrichment on emotionality related behaviours in Huntington's disease transgenic mice
Thibault Renoir et al.
JOURNAL OF PHYSIOLOGY-LONDON (2013)
Probucol Affords Neuroprotection in a 6-OHDA Mouse Model of Parkinson's Disease
Renata Pietsch Ribeiro et al.
NEUROCHEMICAL RESEARCH (2013)
Probucol Increases Striatal Glutathione Peroxidase Activity and Protects against 3-Nitropropionic Acid-Induced Pro-Oxidative Damage in Rats
Dirleise Colle et al.
PLOS ONE (2013)
Light and electron microscopic characterization of the evolution of cellular pathology in YAC128 Huntington's disease transgenic mice
Zubeyde Bayram-Weston et al.
BRAIN RESEARCH BULLETIN (2012)
Probucol modulates oxidative stress and excitotoxicity in Huntington's disease models in vitro
Dirleise Colle et al.
BRAIN RESEARCH BULLETIN (2012)
Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise
Thibault Renoir et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Screening of Therapeutic Strategies for Huntington's Disease in YAC128 Transgenic Mice
Joana M. Gil-Mohapel
CNS NEUROSCIENCE & THERAPEUTICS (2012)
Probucol, a lipid-lowering drug, prevents cognitive and hippocampal synaptic impairments induced by amyloid β peptide in mice
Danubia B. Santos et al.
EXPERIMENTAL NEUROLOGY (2012)
Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice
Mahmoud A. Pouladi et al.
HUMAN MOLECULAR GENETICS (2012)
Deficits in Spermatogenesis but not Neurogenesis are Alleviated by Chronic Testosterone Therapy in R6/1 Huntington's Disease Mice
A. J. Hannan et al.
JOURNAL OF NEUROENDOCRINOLOGY (2012)
Huntington's disease knock-in male mice show specific anxiety-like behaviour and altered neuronal maturation
Sophie Orvoen et al.
NEUROSCIENCE LETTERS (2012)
Psychiatric Disorders in Huntington's Disease: A 2-Year Follow-up Study
W. Reedeker et al.
PSYCHOSOMATICS (2012)
Does Methylmercury-Induced Hypercholesterolemia Play a Causal Role in Its Neurotoxicity and Cardiovascular Disease?
Eduardo Luiz Moreira et al.
TOXICOLOGICAL SCIENCES (2012)
Antidepressant-Like Effect of the Norepinephrine-Dopamine Reuptake Inhibitor Bupropion in a Mouse Model of Huntington's Disease with Dopaminergic Dysfunction
Thibault Renoir et al.
JOURNAL OF HUNTINGTONS DISEASE (2012)
Up-regulation of the isoenzymes MAO-A and MAO-B in the human basal ganglia and pons in Huntington's disease revealed by quantitative enzyme radioautography
Grayson Richards et al.
BRAIN RESEARCH (2011)
Immunohistological markers for proliferative events, gliogenesis, and neurogenesis within the adult hippocampus
Oliver von Bohlen und Halbach
CELL AND TISSUE RESEARCH (2011)
Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease
Jessica M. Simpson et al.
NEUROBIOLOGY OF DISEASE (2011)
Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model
Yong Cheng et al.
NEUROIMAGE (2011)
Combined Treatment with the Mood Stabilizers Lithium and Valproate Produces Multiple Beneficial Effects in Transgenic Mouse Models of Huntington's Disease
Chi-Tso Chiu et al.
NEUROPSYCHOPHARMACOLOGY (2011)
NEUROGENESIS IN THE R6/2 MOUSE MODEL OF HUNTINGTON'S DISEASE IS IMPAIRED AT THE LEVEL OF NEUROD1
V. Fedele et al.
NEUROSCIENCE (2011)
Sexually Dimorphic Serotonergic Dysfunction in a Mouse Model of Huntington's Disease and Depression
Thibault Renoir et al.
PLOS ONE (2011)
Depression in the early stages of Huntington disease
Eric A. Epping et al.
NEURODEGENERATIVE DISEASE MANAGEMENT (2011)
New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?
Wei Deng et al.
NATURE REVIEWS NEUROSCIENCE (2010)
Earliest functional declines in Huntington disease
Leigh J. Beglinger et al.
PSYCHIATRY RESEARCH (2010)
Where are we with probucol: A new life for an old drug?
Shizuya Yamashita et al.
ATHEROSCLEROSIS (2009)
Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin
Mahmoud A. Pouladi et al.
BRAIN (2009)
The R6 lines of transgenic mice: A model for screening new therapies for Huntington's disease
Joana M. Gil et al.
BRAIN RESEARCH REVIEWS (2009)
Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease
Terence Y. C. Pang et al.
HUMAN MOLECULAR GENETICS (2009)
Use of magnetic resonance imaging for anatomical phenotyping of the R6/2 mouse model of Huntington's disease
S. J. Sawiak et al.
NEUROBIOLOGY OF DISEASE (2009)
Probucol Increases Glutathione Peroxidase-1 Activity and Displays Long-Lasting Protection against Methylmercury Toxicity in Cerebellar Granule Cells
Marcelo Farina et al.
TOXICOLOGICAL SCIENCES (2009)
Mechanisms of neurodegeneration in Huntington's disease
Joana M. Gil et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model
Qi Peng et al.
EXPERIMENTAL NEUROLOGY (2008)
Long-Term Probucol Treatment Prevents Secondary Cardiovascular Events: a Cohort Study of Patients with Heterozygous Familial Hypercholesterolemia in Japan
Shizuya Yamashita et al.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2008)
Cross-Sectional Study on Prevalences of Psychiatric Disorders in Mutation Carriers of Huntington's Disease Compared With Mutation-Negative First-Degree Relatives
Erik van Duijn et al.
JOURNAL OF CLINICAL PSYCHIATRY (2008)
Adult Neurogenesis, Mental Health, and Mental Illness: Hope or Hype?
Amelia J. Eisch et al.
JOURNAL OF NEUROSCIENCE (2008)
Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease
Wenzhen Duan et al.
NEUROBIOLOGY OF DISEASE (2008)
Psychiatric symptoms in Huntington's disease before diagnosis: The Predict-HD study
Kevin Duff et al.
BIOLOGICAL PSYCHIATRY (2007)
Beneficial synergistic effects of concurrent treatment with cilostazol and probucol against focal cerebral ischemic injury in rats
So Youn Park et al.
BRAIN RESEARCH (2007)
Physical activity fails to rescue hippocampal neurogenesis deficits in the R6/2 mouse model of Huntington's disease
Zacharias Kohl et al.
BRAIN RESEARCH (2007)
Selective degeneration in YAC mouse models of Huntington disease
Jeremy M. Van Raamsdonk et al.
BRAIN RESEARCH BULLETIN (2007)
Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: effects of environmental enrichment
SE Lazic et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease
JM Van Raamsdonk et al.
HUMAN MOLECULAR GENETICS (2005)
Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice
JMAC Gil et al.
NEUROBIOLOGY OF DISEASE (2005)
Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine
HE Grote et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease
JM Van Raamsdonk et al.
JOURNAL OF NEUROSCIENCE (2005)
Synaptic dysfunction in Huntington's disease: a new perspective
R Smith et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2005)
Decreased hippocampal cell proliferation in R6/1 Huntington's mice
SE Lazic et al.
NEUROREPORT (2004)
Hippocampal volume and depression: A meta-analysis of MRI studies
P Videbech et al.
AMERICAN JOURNAL OF PSYCHIATRY (2004)
Transient expression of doublecortin during adult neurogenesis
JP Brown et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2003)
Huntington's disease: a synaptopathy?
JY Li et al.
TRENDS IN MOLECULAR MEDICINE (2003)
Antidepressant-like effects in various mice strains in the tail suspension test
N Ripoll et al.
BEHAVIOURAL BRAIN RESEARCH (2003)
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
L Santarelli et al.
SCIENCE (2003)
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease
EJ Slow et al.
HUMAN MOLECULAR GENETICS (2003)
Evidence for more widespread cerebral pathology in early HD - An MRI-based morphometric analysis
HD Rosas et al.
NEUROLOGY (2003)
The cholesterol-lowering drug probucol increases apolipoprotein E production in the hippocampus of aged rats: Implications for Alzheimer's disease
D Champagne et al.
NEUROSCIENCE (2003)
Behavioural abnormalities contribute to functional decline in Huntington's disease
JM Hamilton et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2003)
Positron emission tomography imaging in depression: a neural systems perspective
HS Mayberg
NEUROIMAGING CLINICS OF NORTH AMERICA (2003)
The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis
N Kee et al.
JOURNAL OF NEUROSCIENCE METHODS (2002)
Genetic differences in the tail-suspension test and its relationship to imipramine response among 11 inbred strains of mice
XQ Liu et al.
BIOLOGICAL PSYCHIATRY (2001)
Progression of symptoms in the early and middle stages of Huntington disease
SC Kirkwood et al.
ARCHIVES OF NEUROLOGY (2001)
Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro
H Manev et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2001)
The molecular biology of Huntington's disease
LW Ho et al.
PSYCHOLOGICAL MEDICINE (2001)
Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
JE Malberg et al.
JOURNAL OF NEUROSCIENCE (2000)
Adult brain neurogenesis and psychiatry: a novel theory of depression
BL Jacobs et al.
MOLECULAR PSYCHIATRY (2000)