Journal
FRONTIERS OF MEDICINE
Volume 10, Issue 1, Pages 18-27Publisher
SPRINGER
DOI: 10.1007/s11684-015-0427-6
Keywords
hydrogen sulfide; cardiovascular; cancer; hypertension
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Hydrogen sulfide (H2S), a colorless gas smelling of rotten egg, has long been considered a toxic gas and environment hazard. However, evidences show that H2S plays a great role in many physiological and pathological activities, and it exhibits different effects when applied at various doses. In this review, we summarize the chemistry and biomedical applications of H2S-releasing compounds, including inorganic salts, phosphorodithioate derivatives, derivatives of Allium sativum extracts, derivatives of thioaminoacids, and derivatives of antiinflammatory drugs.
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