Journal
JAMA NEUROLOGY
Volume 75, Issue 11, Pages 1331-1337Publisher
AMER MEDICAL ASSOC
DOI: 10.1001/jamaneurol.2018.2101
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Funding
- National Institute of Neurological Disorders and Stroke/National Institutes of Health [U01-NS041588]
- National Institute on Minority Health and Health Disparities/National Institutes of Health [P30MD000502]
- Janssen Pharmaceutical Companies Johnson Johnson
- Boehringer-Ingelheim
- Merck
- Bristol-Myers Squib/Sanofi Pharmaceutical Partnership
- American Heart Association Pharmaceutical Roundtable
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IMPORTANCE Get With The Guidelines-Stroke (GWTG-Stroke) is an American Heart Association/American Stroke Association stroke-care quality-improvement program; however, to our knowledge, there has not been a direct comparison of the quality of care between patients hospitalized at participating hospitals and those at nonparticipating hospitals. OBJECTIVE To contrast quality of stroke care measures for patients admitted to hospitals participating and not participating in GWTG-Stroke. DESIGN, SETTING, AND PARTICIPANTS Subpopulation of 546 participants with ischemic stroke occurring during a 9-year follow-up of the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study, a population-based cohort study of 30 239 randomly selected black and white participants 45 years and older recruited between 2003 and 2007. Of those with stroke, 207 (36%) were treated in a hospital participating in GWTG-Stroke and 339 in a nonparticipating hospital. Data were analyzed between July 29, 2017, and April 17, 2018. MAIN OUTCOMES AND MEASURES Quality of care measures including use of tissue plasminogen activator, performance of swallowing evaluation, antithrombotic use in first 48 hours, lipid profile assessment, discharge receiving antithrombotic therapy, discharge receiving a statin, neurologist evaluation, providing weight loss and exercise counseling, education on stroke risk factors and warning signs, and assessment for rehabilitation. RESULTS Participants treated at participating hospitals had a mean (SD) age of 74 (8) years and 100 of 207 were men (48%). while those seen at nonparticipating hospitals had a mean (SD) age of 73 (9) years, and 161 of 339 were men (48%). Those seen in participating hospitals were more likely to receive 5 of 10 evidence-based interventions recommended for patients hospitalized with ischemic stroke, including receiving tissue plasminogen activator (RR, 3.74; 95% CI, 1.65-8.50), education on risk factors (RR, 1.54; 95% CI, 1.16-2.05), having an evaluation for swallowing (RR, 1.25; 95% CI, 1.04-1.50), a lipid evaluation (RR, 1.18; 95% CI, 1.05-1.32), and an evaluation by a neurologist (RR, 1.12; 95% CI, 1.05-1.20). Those seen in participating hospitals received a mean of 5.4 (95% CI, 5.2-5.6) interventions compared with 4.8 (95% CI, 4.6-5.0) in nonparticipating hospitals (P < .001). CONCLUSIONS AND RELEVANCE These data collected independently of the GWTG-Stroke program document improved stroke care for patients with ischemic stroke hospitalized at participating hospitals.
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