Related references
Note: Only part of the references are listed.From T cell exhaustion to anti-cancer immunity
Gregory Verdeil et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2016)
Identification of Rare High-Avidity, Tumor-Reactive CD8+ T Cells by Monomeric TCR-Ligand Off-Rates Measurements on Living Cells
Michael Hebeisen et al.
CANCER RESEARCH (2015)
T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cells
M. P. Tan et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2015)
TCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicity
Jennifer D. Stone et al.
CURRENT OPINION IN IMMUNOLOGY (2015)
Quantitative TCR:pMHC Dissociation Rate Assessment by NTAmers Reveals Antimelanoma T Cell Repertoires Enriched for High Functional Competence
Philippe O. Gannon et al.
JOURNAL OF IMMUNOLOGY (2015)
Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells
Jinsung Hong et al.
JOURNAL OF IMMUNOLOGY (2015)
Nivolumab and Ipilimumab versus Ipilimumab in Untreated Melanoma
Michael A. Postow et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Pembrolizumab for the Treatment of Non-Small-Cell Lung Cancer
Edward B. Garon et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Pembrolizumab versus Ipilimumab in Advanced Melanoma
Caroline Robert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Neoantigens in cancer immunotherapy
Ton N. Schumacher et al.
SCIENCE (2015)
Engineered T cells for cancer therapy
Carl H. June et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2014)
Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells
G. Dolton et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2014)
2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system
Baoyu Liu et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2014)
Clonotype-specific avidity influences the dynamics and hierarchy of virus-specific regulatory and effector CD4+T-cell responses
Jie Liu et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2014)
CAR-modified anti-CD19 T cells for the treatment of B-cell malignancies: rules of the road
Saar Gill et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2014)
Accumulation of Serial Forces on TCR and CD8 Frequently Applied by Agonist Antigenic Peptides Embedded in MHC Molecules Triggers Calcium in T Cells
Sergey Pryshchep et al.
JOURNAL OF IMMUNOLOGY (2014)
Specific Increase in Potency via Structure-Based Design of a TCR
Karolina Malecek et al.
JOURNAL OF IMMUNOLOGY (2014)
High Avidity CD8+ T Cells Efficiently Eliminate Motile HIV-Infected Targets and Execute a Locally Focused Program of Anti-Viral Function
Maria Hottelet Foley et al.
PLOS ONE (2014)
A sharp T-cell antigen receptor signaling threshold for T-cell proliferation
Byron B. Au-Yeung et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Reproducible selection of high avidity CD8+ T-cell clones following secondary acute virus infection
Tania Cukalac et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
An induced rebinding model of antigen discrimination
Omer Dushek et al.
TRENDS IN IMMUNOLOGY (2014)
Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor
Javier Casas et al.
NATURE COMMUNICATIONS (2014)
Apoptosis-Regulated Low-Avidity Cancer-Specific CD8+ T Cells Can Be Rescued to Eliminate HER2/neu-Expressing Tumors by Costimulatory Agonists in Tolerized Mice
Chelsea M. Black et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)
Ludger Klein et al.
NATURE REVIEWS IMMUNOLOGY (2014)
Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
Gerald P. Linette et al.
BLOOD (2013)
Enhanced-affinity murine T-cell receptors for tumor/self-antigens can be safe in gene therapy despite surpassing the threshold for thymic selection
Thomas M. Schmitt et al.
BLOOD (2013)
Relapse or Eradication of Cancer Is Predicted by Peptide-Major Histocompatibility Complex Affinity
Boris Engels et al.
CANCER CELL (2013)
High-Avidity T Cells Are Preferentially Tolerized in the Tumor Microenvironment
Ziqiang Zhu et al.
CANCER RESEARCH (2013)
Adoptive Transfer of Tumor-Infiltrating Lymphocytes in Patients with Metastatic Melanoma: Intent-to-Treat Analysis and Efficacy after Failure to Prior Immunotherapies
Michal J. Besser et al.
CLINICAL CANCER RESEARCH (2013)
Competition between T cells maintains clonal dominance during memory inflation induced by MCMV
Holly Turula et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
Mixed functional characteristics correlating with TCR-ligand koff-rate of MHC-tetramer reactive T cells within the naive T-cell repertoire
Pleun Hombrink et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
The clinical potential for koff-rate measurement in adoptive immunotherapy
Magdalena Nauerth et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2013)
Design of T-cell receptor libraries with diverse binding properties to examine adoptive T-cell responses
A. S. Chervin et al.
GENE THERAPY (2013)
Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network
Cheng Zhu et al.
IMMUNOLOGICAL REVIEWS (2013)
Mechanical regulation of T-cell functions
Wei Chen et al.
IMMUNOLOGICAL REVIEWS (2013)
SHP-1 phosphatase activity counteracts increased T cell receptor affinity
Michael Hebeisen et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy
Richard A. Morgan et al.
JOURNAL OF IMMUNOTHERAPY (2013)
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells
Clifford S. Guy et al.
NATURE IMMUNOLOGY (2013)
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
Paul F. Robbins et al.
NATURE MEDICINE (2013)
T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy
Shi Zhong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
TCR-Ligand koff Rate Correlates with the Protective Capacity of Antigen-Specific CD8+ T Cells for Adoptive Transfer
Magdalena Nauerth et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Identification of a Titin-Derived HLA-A1-Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3-Directed T Cells
Brian J. Cameron et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Rapid Perturbation in Viremia Levels Drives Increases in Functional Avidity of HIV-specific CD8 T Cells
Selena Vigano et al.
PLOS PATHOGENS (2013)
Molecular insights for optimizing T cell receptor specificity against cancer
Michael Hebeisen et al.
FRONTIERS IN IMMUNOLOGY (2013)
Structure-based, rational design of T cell receptors
V. Zoete et al.
FRONTIERS IN IMMUNOLOGY (2013)
TCR-engineered T cells meet new challenges to treat solid tumors: choice of antigen, T cell fitenss, and sensitization of tumor milieu
Andre Kunert et al.
FRONTIERS IN IMMUNOLOGY (2013)
Analysis, Isolation, and activation of antigen-specific CD4(+) and CD8(+) T cells by soluble MHC-peptide complexes
Julien Schmidt et al.
FRONTIERS IN IMMUNOLOGY (2013)
Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose
Tanja Loevgren et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2012)
TCR signaling requirements for activating T cells and for generating memory
Dietmar Zehn et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Functional Avidity: A Measure to Predict the Efficacy of Effector T Cells?
Selena Vigano et al.
CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2012)
Specific Lymphocyte Subsets Predict Response to Adoptive Cell Therapy Using Expanded Autologous Tumor-Infiltrating Lymphocytes in Metastatic Melanoma Patients
Laszlo G. Radvanyi et al.
CLINICAL CANCER RESEARCH (2012)
Different affinity windows for virus and cancer-specific T-cell receptors: Implications for therapeutic strategies
Milos Aleksic et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2012)
Structural and biophysical determinants of aß T-cell antigen recognition
John S. Bridgeman et al.
IMMUNOLOGY (2012)
The molecular determinants of CD8 co-receptor function
David K. Cole et al.
IMMUNOLOGY (2012)
High-avidity, high-IFNγ-producing CD8 T-cell responses following immune selection during HIV-1 infection
Niamh M. Keane et al.
IMMUNOLOGY AND CELL BIOLOGY (2012)
Interplay between T Cell Receptor Binding Kinetics and the Level of Cognate Peptide Presented by Major Histocompatibility Complexes Governs CD8+ T Cell Responsiveness
Melita Irving et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Human Antitumor CD8+ T Cells Producing Th1 Polycytokines Show Superior Antigen Sensitivity and Tumor Recognition
Susanne Wilde et al.
JOURNAL OF IMMUNOLOGY (2012)
Long-term Persistence of CD4+ but Rapid Disappearance of CD8+ T Cells Expressing an MHC Class I-restricted TCR of Nanomolar Affinity
Boris Engels et al.
MOLECULAR THERAPY (2012)
Safety and Activity of Anti-PD-L1 Antibody in Patients with Advanced Cancer
Julie R. Brahmer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer
Suzanne L. Topalian et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Trafficking of High Avidity HER-2/neu-Specific T Cells into HER-2/neu-Expressing Tumors after Depletion of Effector/Memory-Like Regulatory T Cells
Vivian L. Weiss et al.
PLOS ONE (2012)
High Avidity Cytotoxic T Lymphocytes Can Be Selected into the Memory Pool but They Are Exquisitely Sensitive to Functional Impairment
Victoria A. Brentville et al.
PLOS ONE (2012)
Insights into T cell recognition of antigen: significance of two-dimensional kinetic parameters
Lindsay J. Edwards et al.
FRONTIERS IN IMMUNOLOGY (2012)
Functional differences between low- and high-affinity CD8+ T cells in the tumor environment
Rinke Bos et al.
ONCOIMMUNOLOGY (2012)
Adoptive immunotherapy for cancer: harnessing the T cell response
Nicholas P. Restifo et al.
NATURE REVIEWS IMMUNOLOGY (2012)
Prognostic and Predictive Impact of Intra- and Peritumoral Immune Infiltrates
Wolf Herman Fridman et al.
CANCER RESEARCH (2011)
Determinants of Successful CD8+ T-Cell Adoptive Immunotherapy for Large Established Tumors in Mice
Christopher A. Klebanoff et al.
CLINICAL CANCER RESEARCH (2011)
Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy
Steven A. Rosenberg et al.
CLINICAL CANCER RESEARCH (2011)
Two-Stage Cooperative T Cell Receptor-Peptide Major Histocompatibility Complex-CD8 Trimolecular Interactions Amplify Antigen Discrimination
Ning Jiang et al.
IMMUNITY (2011)
Reversible Major Histocompatibility Complex I-Peptide Multimers Containing Ni2+-Nitrilotriacetic Acid Peptides and Histidine Tags Improve Analysis and Sorting of CD8+ T Cells
Julien Schmidt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1
Paul F. Robbins et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Strength of TCR-Peptide/MHC Interactions and In Vivo T Cell Responses
Emily Corse et al.
JOURNAL OF IMMUNOLOGY (2011)
TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms
Oleg Y. Borbulevych et al.
JOURNAL OF IMMUNOLOGY (2011)
Cancer immunotherapy comes of age
Ira Mellman et al.
NATURE (2011)
Cell transfer immunotherapy for metastatic solid cancer-what clinicians need to know
Steven A. Rosenberg
NATURE REVIEWS CLINICAL ONCOLOGY (2011)
Ipilimumab plus Dacarbazine for Previously Untreated Metastatic Melanoma
Caroline Robert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Single cell analysis reveals similar functional competence of dominant and nondominant CD8 T-cell clonotypes
Daniel E. Speiser et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Immunotherapy of Malignant Disease with Tumor Antigen-Specific Monoclonal Antibodies
Michael Campoli et al.
CLINICAL CANCER RESEARCH (2010)
Dependence of T Cell Antigen Recognition on T Cell Receptor-Peptide MHC Confinement Time
Milos Aleksic et al.
IMMUNITY (2010)
Molecular immunology lessons from therapeutic T-cell receptor gene transfer
Sharyn Thomas et al.
IMMUNOLOGY (2010)
Ca2+ Release from the Endoplasmic Reticulum of NY-ESO-1-Specific T Cells Is Modulated by the Affinity of TCR and by the Use of the CD8 Coreceptor
Ji-Li Chen et al.
JOURNAL OF IMMUNOLOGY (2010)
Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function
Daphne A. Schmid et al.
JOURNAL OF IMMUNOLOGY (2010)
MM-GBSA binding free energy decomposition and T cell receptor engineering
V. Zoete et al.
JOURNAL OF MOLECULAR RECOGNITION (2010)
The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness
Jun Huang et al.
NATURE (2010)
TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity
Johannes B. Huppa et al.
NATURE (2010)
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
F. Stephen Hodi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
T-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APC
Leandro J. Carreno et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Fast on-rates allow short dwell time ligands to activate T cells
Christopher C. Govern et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery
Maxim N. Artyomov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Goldilocks Model for TCR-Too Much Attraction Might Not Be Best for Vaccine Design
Jill E. Slansky et al.
PLOS BIOLOGY (2010)
Attenuated T Cell Responses to a High-Potency Ligand In Vivo
Emily Corse et al.
PLOS BIOLOGY (2010)
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
Laura A. Johnson et al.
BLOOD (2009)
The duration of TCR/pMHC interactions regulates CTL effector function and tumor-killing capacity
Erick Riquelme et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity
Jennifer D. Stone et al.
IMMUNOLOGY (2009)
Allorestricted T lymphocytes with a high avidity T-cell receptor towards NY-ESO-1 have potent anti-tumor activity
Holger Kroenig et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
In Situ Cytotoxic and Memory T Cells Predict Outcome in Patients With Early-Stage Colorectal Cancer
Franck Pages et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Minimally Cultured or Selected Autologous Tumor-infiltrating Lymphocytes After a Lympho-depleting Chemotherapy Regimen in Metastatic Melanoma Patients
Michal J. Besser et al.
JOURNAL OF IMMUNOTHERAPY (2009)
Complete but curtailed T-cell response to very low-affinity antigen
Dietmar Zehn et al.
NATURE (2009)
Ocular and Systemic Autoimmunity after Successful Tumor-Infiltrating Lymphocyte Immunotherapy for Recurrent, Metastatic Melanoma
Steven Yeh et al.
OPHTHALMOLOGY (2009)
Structure-based design of a T-cell receptor leads to nearly 100-fold improvement in binding affinity for pepMHC
Jaafar N. Haidar et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2009)
Affinity threshold for thymic selection through a T-cell receptor-co-receptor zipper
Ed Palmer et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Loss of CTL function among high-avidity tumor-specific CD8+ T cells following tumor infiltration
Claire N. Janicki et al.
CANCER RESEARCH (2008)
Adoptive Cell Therapy for Patients With Metastatic Melanoma: Evaluation of Intensive Myeloablative Chemoradiation Preparative Regimens
Mark E. Dudley et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Avidity maturation of memory CD8 T cells is limited by self-antigen expression
Michael J. Turner et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions
Paul F. Robbins et al.
JOURNAL OF IMMUNOLOGY (2008)
Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity
Douglas C. Palmer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
High-affinity TCRs generated by phage display provide CD4+ T cells with the ability to recognize and kill tumor cell lines
Yangbing Zhao et al.
JOURNAL OF IMMUNOLOGY (2007)
CD8+ T cell activation is governed by TCR-Peptide/MHC affinity, not dissociation rate
Shaomin Tian et al.
JOURNAL OF IMMUNOLOGY (2007)
Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties
Bruno Laugel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Mobilizing the low-avidity T cell repertoire to kill tumors
Rachel H. McMahan et al.
SEMINARS IN CANCER BIOLOGY (2007)
The half-life of the T-cell receptor/peptide-major histocompatibility complex interaction can modulate T-cell activation in response to bacterial challenge
Leandro J. Carreno et al.
IMMUNOLOGY (2007)
Avidity of CD8 T cells sharpens immunodominance
Amiran H. Dzutsev et al.
INTERNATIONAL IMMUNOLOGY (2007)
Reversible HLA multimers (Streptamers) for the isolation of human cytotoxic T lymphocytes functionally active against tumor- and virus-derived antigens
Julia Neudorfer et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2007)
Potent T cell agonism mediated by a very rapid TCR/pMHC interaction
Jonathan M. Boulter et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8+ T cell responses
Nicole L. La Gruta et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
Cancer regression in patients after transfer of genetically engineered lymphocytes
Richard A. Morgan et al.
SCIENCE (2006)
Fluorescence-activated cell sorting and cloning of bona fide CD8+ CTL with reversible MHC-peptide and antibody Fab' conjugates
Philippe Guillaume et al.
JOURNAL OF IMMUNOLOGY (2006)
T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity
Dietmar Zehn et al.
IMMUNITY (2006)
Cytotoxic T lymphocytes kill multiple targets simultaneously via spatiotemporal uncoupling of lytic and stimulatory synapses
Aurelie Wiedemann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity
SM Dunn et al.
PROTEIN SCIENCE (2006)
Soluble MHC-peptide complexes containing long rigid linkers abolish CTL-mediated cytotoxicity
Georgi S. Angelov et al.
JOURNAL OF IMMUNOLOGY (2006)
Avidity for antigen shapes clonal dominance in CD8+T cell populations specific for persistent DNA viruses
DA Price et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Selection of T cell clones expressing high-affinity public TCRs within human cytomegalovirus-specific CD8 T cell responses
L Trautmann et al.
JOURNAL OF IMMUNOLOGY (2005)
Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface
L Wooldridge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
CD8+ cytotoxic T lymphocyte activation by soluble major histocompatibility complex-peptide dimers
M Cebecauer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell
PA González et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Directed evolution of human T-cell receptors with picomolar affinities by phage display
Y Li et al.
NATURE BIOTECHNOLOGY (2005)
High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3
LK Chlewicki et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties
L Malherbe et al.
IMMUNITY (2004)
Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction:: Manifestation of a dual activation threshold
M Faroudi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Caveats in the design of MHC class I tetramer/antigen-specific T lymphocytes dissociation assays
XCL Wang et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2003)
Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells
WW Overwijk et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation
PD Holler et al.
IMMUNITY (2003)
TCRs with high affinity for foreign pMHC show self-reactivity
PD Holler et al.
NATURE IMMUNOLOGY (2003)
Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma
P Romero et al.
IMMUNOLOGICAL REVIEWS (2002)
Reversible MHC multimer staining for functional isolation of T-cell populations and effective adoptive transfer
M Knabel et al.
NATURE MEDICINE (2002)
Functional avidity of tumor antigen-specific CTL recognition directly correlates with the stability of MHC/peptide multimer binding to TCR
V Dutoit et al.
JOURNAL OF IMMUNOLOGY (2002)
Manipulation of avidity to improve effectiveness of adoptively transferred CD8+ T cells for melanoma immunotherapy in human MHC class I-transgenic mice
TNJ Bullock et al.
JOURNAL OF IMMUNOLOGY (2001)
The impact of duration versus extent of TCR occupancy on T cell activation: A revision of the kinetic proofreading model
C Rosette et al.
IMMUNITY (2001)
Efficient cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex
AM Kalergis et al.
NATURE IMMUNOLOGY (2001)
High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL
MA Derby et al.
JOURNAL OF IMMUNOLOGY (2001)
Melanocyte destruction after antigen-specific immunotherapy of melanoma: Direct evidence of T cell-mediated vitiligo
C Yee et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
T cells compete for access to antigen-bearing antigen-presenting cells
RM Kedl et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
In vitro evolution of a T cell receptor with high affinity for peptide/MHC
PD Holler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Share Paper
