Journal
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY
Volume 17, Issue 2, Pages 185-188Publisher
KOREAN SOC NEUROGASTERONTEROL & MOTILITY
DOI: 10.5056/jnm.2011.17.2.185
Keywords
Breath tests; Constipation; Hydrogen; Irritable bowel syndrome; Methane
Categories
Funding
- Department of Science and Technology, Government of India [SR/S0/HS/-15/2007]
Ask authors/readers for more resources
Constipation, a common problem in gastroenterology practice, may result from slow colonic transit. Therapeutic options for slow transit constipations are limited. Excessive methane production by the methanogenic gut flora, which is more often found in patients with constipation, slows colonic transit. Thus, reduction in methane production with antibiotic treatment directed against methanogenic flora of the gut may accelerate colonic transit resulting in improvement in constipation. However, there is not much data to prove this hypothesis. We, therefore, report a patient with slow transit constipation associated with high methane production both in fasting state and after ingestion of glucose, whose constipation improved after treatment with non-absorbable antibiotic, rifaximin, which reduced breath methane values.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available