Journal
JOURNAL OF MATERIALS CHEMISTRY B
Volume 1, Issue 38, Pages 5128-5136Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3tb20851f
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A droplet-based microfluidics technique is used to produce monodisperse, 80 mm collagen-gelatin beads with tunable mechanical properties in the range of 1-10 kPa after photo-crosslinking. The gel beads are porous, mechanically robust and stable in buffer, but can be degraded enzymatically. Encapsulated fibroblast cells maintain 70% viability after one-week encapsulation and preliminary results show that the degree of spreading of cells in gels is correlated with the stiffness of the material.
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