Journal
JOURNAL OF MATERIALS CHEMISTRY B
Volume 1, Issue 19, Pages 2496-2501Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3tb20144a
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Funding
- National Basic Research Program of China [2010CB732403]
- National Natural Science Foundation of China [21125524, 20975023]
- Program for New Century Excellent Talents in University of China [09-0014]
- Program for Changjiang Scholars and Innovative Research Team in University [IRT1116]
- National Science Foundation of Fujian Province [2010J06003]
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Nowadays, bacterial infection is very common in the world. As a result of overusing antibiotics, several human pathogenic bacteria have become resistant to most of the clinically approved antibiotics. This has created an urgent need for the development of new methods to kill pathogenic bacteria. Here, we describe a novel method for the selective killing of pathogenic bacteria using antibody functionalized nanoscale reduced graphene oxide (NRGO). The antibody-NRGO complex exhibited little toxicity without near-infrared (NIR) irradiation. However, when irradiated with a NIR laser at a low power density (400 mW cm(-2)), the antibody-NRGO complex exhibited excellent photothermal properties and killed captured pathogenic bacteria specifically.
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