Journal
JOURNAL OF MATERIALS CHEMISTRY B
Volume 1, Issue 4, Pages 429-431Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2tb00287f
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Funding
- National Cancer Center grant from the Republic of Korea [1010150-3]
- Pioneer Research Center Program through the National Research Foundation of Korea
- Ministry of Education, Science and Technology, Republic of Korea [2012-0001081]
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Photosensitizers conjugated with hyaluronic acid via disulfide linkers were developed for biologically activatable near-infrared fluorescence imaging and photodynamic therapy. The nanoparticles prepared from the conjugate are nonfluorescent and nonphototoxic in their native state, but become highly fluorescent and phototoxic in response to reductive agents inside cancer cells.
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