Journal
JOURNAL OF MATERIALS CHEMISTRY A
Volume 2, Issue 45, Pages 19131-19135Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ta05013d
Keywords
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Funding
- National Research Fund for Fundamental Key Projects [2011CB935700, 2013CB932802]
- National Natural Science Foundation [21201170, 11290163, 21121001, 91127025, 21171171]
- Key Research Program of the Chinese Academy of Sciences [KJZD-EW-M01]
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A sensitive nano-device for D-glucose detection is prepared by modifying a single conical polymer nanochannel with GOx enzymes. The current-voltage (I-V) characterization suggests that the nano-device responds to D-glucose rather than its enantiomer at concentrations down to 1 nM (10(-9) mol L-1). Moreover, the nano-device exhibits good reproducibility and specificity for D-glucose and is an ideal candidate for commercial non-invasive blood glucose meters in the future.
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