Journal
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
Volume 29, Issue 2, Pages 244-255Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.bpobgyn.2014.06.010
Keywords
hypertensive disorders of pregnancy; gestational diabetes mellitus; preterm birth; fetal growth restriction; metabolic complications; cardiovascular diseases
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There is cumulating evidence linking the occurrence of pregnancy complications, including miscarriage, stillbirth, hypertensive disorders of pregnancy, gestational diabetes mellitus, preterm birth, and fetal growth restriction, with increased future risk of type 2 diabetes mellitus, and hospitalization and death due to cardiovascular and cerebrovascular diseases. Such association is largely related to genetic predisposition and shared pathophysiological mechanisms and changes, which may precede the index pregnancy. Awareness of this association would allow identification of the at-risk women for implementation of preventive measures to reduce the recurrence risk of these complications and mitigate the future development of metabolic and cardiovascular diseases worldwide. (C) 2014 Elsevier Ltd. All rights reserved.
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