Related references
Note: Only part of the references are listed.Incomplete restoration of Mpl expression in the mpl-/- mouse produces partial correction of the stem cell-repopulating defect and paradoxical thrombocytosis
Brian J. Lannutti et al.
BLOOD (2009)
Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mp1 in platelets and terminally differentiated megakaryocytes
Ralph Tiedt et al.
BLOOD (2009)
Mutational inhibition of c-Myb or p300 ameliorates treatment-induced thrombocytopenia
Douglas J. Hilton et al.
BLOOD (2009)
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
James W. Vardiman et al.
BLOOD (2009)
Familial thrombocytosis caused by the novel germ-line mutation p.Pro106Leu in the MPL gene
El-Harith Abdelghaffar El-Harith et al.
BRITISH JOURNAL OF HAEMATOLOGY (2009)
Ligand-independent Thrombopoietin Mutant Receptor Requires Cell Surface Localization for Endogenous Activity
Caroline Marty et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice
Maria Kauppi et al.
BLOOD (2008)
Thrombocytosis and leukocytosis interaction in vascular complications of essential thrombocythemia
Alessandra Carobbio et al.
BLOOD (2008)
Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice
Shu Xing et al.
BLOOD (2008)
Characteristics and clinical correlates of MPL 515W>L/K mutation in essential thrombocythemia
Alessandro M. Vannucchi et al.
BLOOD (2008)
MPL mutations in myeloproliferative disorders:: analysis of the PT-1 cohort
Philip A. Beer et al.
BLOOD (2008)
Increased risks of polycythemia vera, essential thrombocythemia, and myelofibrosis among 24 577 first-degree relatives of 11 039 patients with myeloproliferative neoplasms in Sweden
Ola Landgren et al.
BLOOD (2008)
Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice
Ralph Tiedt et al.
BLOOD (2008)
Rapid detection of MPL Baltimore using LightCycler((R)) technology and melting curve analysis
Graham Standen et al.
BRITISH JOURNAL OF HAEMATOLOGY (2008)
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors
Jun Lu et al.
DEVELOPMENTAL CELL (2008)
Genetic profiling of myeloproliferative disorders by single-nucleotide polymorphism oligonucleotide microarray
Norihiko Kawamata et al.
EXPERIMENTAL HEMATOLOGY (2008)
A de novo splice donor mutation in the thrombopoietin gene causes hereditary thrombocythemia in a Polish family
Kun Liu et al.
HAEMATOLOGICA (2008)
New mutations of MPL in primitive myelofibrosis:: only the MPL W515 mutations promote a G1/S-phase transition
R. Chaligne et al.
LEUKEMIA (2008)
Historical review: megakaryopoiesis and thrombopoiesis
Kenneth Kaushansky
BLOOD (2008)
Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F
K. Shide et al.
LEUKEMIA (2008)
JAK2V617F mutation status identifies subtypes of refractory anemia with ringed sideroblasts associated with marked thrombocytosis
Annette H. Schmitt-Graeff et al.
HAEMATOLOGICA (2007)
JAK2V617F-negative ET patients do not display constitutively active JAK/STAT signaling
Sven Schwernmers et al.
EXPERIMENTAL HEMATOLOGY (2007)
Different STAT-3 and STAT-5 phosphorylation discriminates among Ph-negative chronic myeloproliferative diseases and is independent of the V617F JAK-2 mutation
Luciana Teofili et al.
BLOOD (2007)
Programmed anuclear cell death delimits platelet life span
Kylie D. Mason et al.
CELL (2007)
Markers of myeloproliferative diseases in childhood polycythemia vera and essential thrombocythemia
Luciana Teofili et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis
Linda M. Scott et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Mechanisms of disease: The myeloproliferative disorders
Peter J. Campbell et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Molecular mimicry in the chronic myeloproliferative disorders: reciprocity between quantitative JAK2 V617F and Mpl expression
Alison R. Moliterno et al.
BLOOD (2006)
MPL515 mutations in myeloproliferative and other myeloid disorders:: a study of 1182 patients
Animesh D. Pardanani et al.
BLOOD (2006)
A family with hereditary thrombocythaemia and normal genes for thrombopoietin and c-Mpl
N. Tecuceanu et al.
BRITISH JOURNAL OF HAEMATOLOGY (2006)
Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not essential thrombocythemia
Linda M. Scott et al.
BLOOD (2006)
MPLW515L is anovel somatic activating mutation in myelofibrosis with myeloid metaplasia
Yana Pikman et al.
PLOS MEDICINE (2006)
Genetic and clinical implications of the Val617Phe JAK2 mutation in 72 families with myeloproliferative disorders
Christine Bellanne-Chantelot et al.
BLOOD (2006)
An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor
J Staerk et al.
BLOOD (2006)
c-Myb and p300 regulate stem cell proliferation an hematopoietic differentiation
ML Sandberg et al.
DEVELOPMENTAL CELL (2005)
Suppressor screen in Mpl-/- mice:: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling
MR Carpinelli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Current concepts - Thrombocytosis
AI Schafer
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Mpl Baltimore: A thrombopoietin receptor polymorphism associated with thrombocytosis
AR Moliterno et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin
F Ding et al.
BLOOD (2004)
Clonal hematopoiesis in familial polycythemia vera suggests the involvement of multiple mutational events in the early pathogenesis of the disease
R Kralovics et al.
BLOOD (2003)
Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders
R Kralovics et al.
BLOOD (2003)
Prominent role of TGF-β1 in thrombopoietin-induced myelofibrosis in mice
H Chagraoui et al.
BLOOD (2002)
Hereditary thrombocythaemia is a genetically heterogenous disorder: exclusion of TPO and MPL in two families with hereditary thrombocythaemia
A Wiestner et al.
BRITISH JOURNAL OF HAEMATOLOGY (2000)
Myeloproliferative disorders: complications, survival and causes of death
S Brodmann et al.
ANNALS OF HEMATOLOGY (2000)