Journal
GENOME BIOLOGY
Volume 13, Issue 10, Pages -Publisher
BMC
DOI: 10.1186/gb-2012-13-10-175
Keywords
epigenetics; epigenomics; epitranscriptome; m(6)A; methyl-6-adenosine; methyladenosine; N6-methyladenosine; RNA modifications
Funding
- Starr Cancer Consortium grant [I4-A442]
- National Institutes of Health [I4-A442, I4-A411, 1R01NS076465-02]
- NINDS [NS56306]
- Tri-Institutional Training Program in Computational Biology and Medicine
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R01NS076465, R01NS056306] Funding Source: NIH RePORTER
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Recent studies have found methyl-6-adenosine in thousands of mammalian genes, and this modification is most pronounced near the beginning of the 3'UTR. We present a perspective on current work and new single-molecule sequencing methods for detecting RNA base modifications.
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