4.4 Review

The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities

Journal

GENOME BIOLOGY
Volume 13, Issue 6, Pages -

Publisher

BMC
DOI: 10.1186/gb4029

Keywords

Epigenomics; DNA methylation; life course; longitudinal studies

Funding

  1. Clinical Investigator Program at University of British Columbia
  2. GEoCoDE (EUFP7)
  3. MRC
  4. Wellcome Trust
  5. NIH
  6. BBSRC
  7. EUFP7
  8. NIHR
  9. BBSRC [BB/I025751/1, BB/I025263/1] Funding Source: UKRI
  10. MRC [MC_U123092720] Funding Source: UKRI
  11. Biotechnology and Biological Sciences Research Council [BB/I025263/1, BB/I025751/1] Funding Source: researchfish
  12. Medical Research Council [MC_U123092720] Funding Source: researchfish

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Longitudinal cohort studies are ideal for investigating how epigenetic patterns change over time and relate to changing exposure patterns and the development of disease. We highlight the challenges and opportunities in this approach.

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