Journal
GENOME BIOLOGY
Volume 13, Issue 4, Pages -Publisher
BMC
DOI: 10.1186/gb-2012-13-4-244
Keywords
Human height; mutation effects; mutation-selection balance
Funding
- Australian Research Council [DP1093502]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [P01GM099568] Funding Source: NIH RePORTER
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Much of the heritability for human stature is caused by mutations of small-to-medium effect. This is because detrimental pleiotropy restricts large-effect mutations to very low frequencies.
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