4.4 Article

Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

Journal

GENOME BIOLOGY
Volume 9, Issue 9, Pages -

Publisher

BMC
DOI: 10.1186/gb-2008-9-9-r139

Keywords

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Funding

  1. Marie Curie Canceromics [MEXT-CT-2003-2728]
  2. EU, EU-EPITRON [LSHC-CT2005- 518417]
  3. Cancer Organizations of Finland
  4. Sigrid Juselius Foundation
  5. Turku TE-Centre
  6. Academy of Finland (SysBio) [5207532]
  7. Centres of Excellence [213502]
  8. Emil Aaltonen Foundation
  9. Foundation of Technology
  10. Finnish Konkordia Fund and the Foundation

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Our knowledge on tissue- and disease-specific functions of human genes is rather limited and highly context-specific. Here, we have developed a method for the comparison of mRNA expression levels of most human genes across 9,783 Affymetrix gene expression array experiments representing 43 normal human tissue types, 68 cancer types, and 64 other diseases. This database of gene expression patterns in normal human tissues and pathological conditions covers 113 million datapoints and is available from the GeneSapiens website.

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