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Intron mis-splicing: no alternative?

Journal

GENOME BIOLOGY
Volume 9, Issue 2, Pages -

Publisher

BIOMED CENTRAL LTD
DOI: 10.1186/gb-2008-9-2-208

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Funding

  1. Intramural NIH HHS Funding Source: Medline

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A recent report reveals widespread mis-splicing of RNA transcripts in eukaryotes, with mis-spliced RNA destroyed by nonsense-mediated mRNA decay. This striking inefficiency deepens the mystery of the proliferation and persistence of introns.

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