Journal
FRONTIERS IN PLANT SCIENCE
Volume 5, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fpls.2014.00328
Keywords
Arabidopsis; auxin gradient; root development; stem cell niche; computational modeling
Categories
Funding
- North Carolina Agricultural Research Service
- North Carolina State University Provost's Office
- Mathematical Biology Research Training Group
- Division Of Mathematical Sciences
- Direct For Mathematical & Physical Scien [1246991] Funding Source: National Science Foundation
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The presence of an auxin gradient in the Arabidopsis root is crucial for proper root development and importantly, for stem cell niche (SCN) maintenance. Subsequently, developmental pathways in the root SCN regulate the formation of the auxin gradient. Combinations of experimental data and computational modeling enable the identification of pathways involved in establishing and maintaining the auxin gradient. We describe how the predictive power of these computational models is used to find how genes and their interactions tightly control the formation of an auxin maximum in the SCN. In addition, we highlight known connections between signaling pathways involving auxin and controlling patterning and development in Arabidopsis.
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