Journal
FRONTIERS IN MICROBIOLOGY
Volume 1, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fmicb.2010.00134
Keywords
history of antibiotic discovery; antibiotic resistance; novel antimicrobials; prevention of antibiotic resistance; environmental resistome
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Funding
- Scottish Government Rural and Environment Research and Analysis Directorate
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This article gives a very brief overview of the antibiotic era, beginning from the discovery of first antibiotics until the present day situation, which is marred by the emergence of hard-to-treat multiple antibiotic-resistant infections. The ways of responding to the antibiotic resistance challenges such as the development of novel strategies in the search for new antimicrobials, designing more effective preventive measures and, importantly, better understanding the ecology of antibiotics and antibiotic resistance are discussed. The expansion of conceptual frameworks based on recent developments in the field of antimicrobials, antibiotic resistance, and chemotherapy is also discussed.
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