Related references
Note: Only part of the references are listed.Protein Dynamics in Complex DNA Lesions
Radoslav Aleksandrov et al.
MOLECULAR CELL (2018)
NAD(+) analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains
Marie-France Langelier et al.
NATURE COMMUNICATIONS (2018)
High speed of fork progression induces DNA replication stress and genomic instability
Apolinar Maya-Mendoza et al.
NATURE (2018)
Global DNA dynamics of 8-oxoguanine repair by human OGG1 revealed by stopped-flow kinetics and molecular dynamics simulation
M. V. Lukina et al.
MOLECULAR BIOSYSTEMS (2017)
PARP1 changes from three-dimensional DNA damage searching to one-dimensional diffusion after auto-PARylation or in the presence of APE1
Lili Liu et al.
NUCLEIC ACIDS RESEARCH (2017)
Single molecule detection of PARP1 and PARP2 interaction with DNA strand breaks and their poly(ADP-ribosyl)ation using high-resolution AFM imaging
Maria V. Sukhanova et al.
NUCLEIC ACIDS RESEARCH (2016)
Readers of poly(ADP-ribose): designed to be fit for purpose
Federico Teloni et al.
NUCLEIC ACIDS RESEARCH (2016)
PARP inhibitors: the race is on
Jessica S. Brown et al.
BRITISH JOURNAL OF CANCER (2016)
New directions in poly(ADP-ribose) polymerase biology
Florian J. Bock et al.
FEBS JOURNAL (2016)
Laying a trap to kill cancer cells: PARP inhibitors and their mechanisms of action
Yves Pommier et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
PARP inhibitors: A new era of targeted therapy
Shifalika Tangutoori et al.
MATURITAS (2015)
Mechanistic Dissection of PARP1 Trapping and the Impacton In Vivo Tolerability and Efficacy of PARP Inhibitors
Todd A. Hopkins et al.
MOLECULAR CANCER RESEARCH (2015)
Biology of Poly(ADP-Ribose) Polymerases: The Factotums of Cell Maintenance
Peter Bai
MOLECULAR CELL (2015)
Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation
Eva Barkauskaite et al.
MOLECULAR CELL (2015)
The Promise of Proteomics for the Study of ADP-Ribosylation
Florian J. Bock et al.
MOLECULAR CELL (2015)
Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1
Sebastian Eustermann et al.
MOLECULAR CELL (2015)
PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain
Jennine M. Dawicki-McKenna et al.
MOLECULAR CELL (2015)
Balancing between affinity and speed in target DNA search by zinc-finger proteins via modulation of dynamic conformational ensemble
Levani Zandarashvili et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Trapping Poly(ADP-Ribose) Polymerase
Yuqiao Shen et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Review of Poly (ADP-ribose) Polymerase (PARP) Mechanisms of Action and Rationale for Targeting in Cancer and Other Diseases
Julio C. Morales et al.
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION (2014)
Structure and function of the ARH family of ADP-ribosyl-acceptor hydrolases
Masato Mashimo et al.
DNA REPAIR (2014)
Poly(ADP-ribose) polymerases in double-strand break repair: Focus on PARP1, PARP2 and PARP3
Carole Beck et al.
EXPERIMENTAL CELL RESEARCH (2014)
PARP inhibitors in ovarian cancer: Current status and future promise
Joyce F. Liu et al.
GYNECOLOGIC ONCOLOGY (2014)
PARP-2 and PARP-3 are selectively activated by 5' phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1
Marie-France aEuro Langelier et al.
NUCLEIC ACIDS RESEARCH (2014)
Automodification switches PARP-1 function from chromatin architectural protein to histone chaperone
Uma M. Muthurajan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling
Tobias Karlberg et al.
MOLECULAR ASPECTS OF MEDICINE (2013)
The diverse roles and clinical relevance of PARPs in DNA damage repair: Current state of the art
Mike De Vos et al.
BIOCHEMICAL PHARMACOLOGY (2012)
Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors
Junko Murai et al.
CANCER RESEARCH (2012)
Alternative Modes of Binding of Poly(ADP-ribose) Polymerase 1 to Free DNA and Nucleosomes
Nicholas J. Clark et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Structural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1
Marie-France Langelier et al.
SCIENCE (2012)
Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY
Marie-France Langelier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Facilitated DNA Search by Multidomain Transcription Factors: Cross Talk via a Flexible Linker
Dana Vuzman et al.
BIOPHYSICAL JOURNAL (2010)
The Zn3 Domain of Human Poly(ADP-ribose) Polymerase-1 (PARP-1) Functions in Both DNA-dependent Poly(ADP-ribose) Synthesis Activity and Chromatin Compaction
Marie-France Langelier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Searching DNA via a Monkey Bar Mechanism: The Significance of Disordered Tails
Dana Vuzman et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Application of Stopped-flow Kinetics Methods to Investigate the Mechanism of Action of a DNA Repair Protein
F. Noah Biro et al.
Jove-Journal of Visualized Experiments (2010)
An end to 40 years of mistakes in DNA-protein association kinetics?
Stephen E. Halford
BIOCHEMICAL SOCIETY TRANSACTIONS (2009)
Binding Kinetics and Activity of Human Poly(ADP-ribose) Polymerase-1 on Oligo-Deoxyribonucleotide Substrates
Timothy J. Jorgensen et al.
JOURNAL OF MOLECULAR RECOGNITION (2009)
How a protein searches for its site on DNA: the mechanism of facilitated diffusion
Leonid Mirny et al.
JOURNAL OF PHYSICS A-MATHEMATICAL AND THEORETICAL (2009)
PCR-mediated deletion of plasmid DNA
Mattlas D. Hansson et al.
ANALYTICAL BIOCHEMISTRY (2008)
Global jumping and domain-specific intersegment transfer between DNA cognate sites of the multidomain transcription factor Oct-1
Michaeleen Doucleff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells
Oliver Mortusewicz et al.
NUCLEIC ACIDS RESEARCH (2007)
NMR structural and kinetic characterization of a homeodomain diffusing and hopping on nonspecific DNA
Junji Iwahara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1
MY Kim et al.
CELL (2004)
How do site-specific DNA-binding proteins find their targets?
SE Halford et al.
NUCLEIC ACIDS RESEARCH (2004)
A protein-DNA binding mechanism proceeds through multi-state or two-state parallel pathways
DU Ferreiro et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)