Journal
ELIFE
Volume 7, Issue -, Pages -Publisher
ELIFE SCIENCES PUBLICATIONS LTD
DOI: 10.7554/eLife.36520
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Funding
- National Institute on Drug Abuse [DA038725, R01 DA033396]
- National Institute of Mental Health [F31 MH101956]
- National Institute of Biomedical Imaging and Bioengineering [R01 EB003320]
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Though the last decade has seen accelerated advances in techniques and technologies to perturb neuronal circuitry in the brain, we are still poorly equipped to adequately dissect endogenous peptide release in vivo. To this end we developed a system that combines in vivo optogenetics with microdialysis and a highly sensitive mass spectrometry-based assay to measure opioid peptide release in freely moving rodents.
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