Related references
Note: Only part of the references are listed.The promise and challenge of high-throughput sequencing of the antibody repertoire
George Georgiou et al.
NATURE BIOTECHNOLOGY (2014)
Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection
Noah J. Tubo et al.
CELL (2013)
T cell responses to antigen: hasty proposals resolved through long engagements
Karen Tkach et al.
CURRENT OPINION IN IMMUNOLOGY (2013)
Antigen Availability Determines CD8+ T Cell-Dendritic Cell Interaction Kinetics and Memory Fate Decisions
Sarah E. Henrickson et al.
IMMUNITY (2013)
A Single Peptide-Major Histocompatibility Complex Ligand Triggers Digital Cytokine Secretion in CD4+ T Cells
Jun Huang et al.
IMMUNITY (2013)
Coupled IL-2-Dependent Extracellular Feedbacks Govern Two Distinct Consecutive Phases of CD4 T Cell Activation
Nir Waysbort et al.
JOURNAL OF IMMUNOLOGY (2013)
Dynamic regulatory network controlling TH17 cell differentiation
Nir Yosef et al.
NATURE (2013)
Phenotypic model for early T-cell activation displaying sensitivity, specificity, and antagonism
Paul Francois et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Cell-to-Cell Variability Analysis Dissects the Plasticity of Signaling of Common γ Chain Cytokines in T Cells
Jesse W. Cotari et al.
SCIENCE SIGNALING (2013)
Marginating Dendritic Cells of the Tumor Microenvironment Cross-Present Tumor Antigens and Stably Engage Tumor-Specific T Cells
John J. Engelhardt et al.
CANCER CELL (2012)
The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude
Marc K. Jenkins et al.
JOURNAL OF IMMUNOLOGY (2012)
Cytokines of the γc family control CD4+ T cell differentiation and function
Hidehiro Yamane et al.
NATURE IMMUNOLOGY (2012)
Generic Indicators for Loss of Resilience Before a Tipping Point Leading to Population Collapse
Lei Dai et al.
SCIENCE (2012)
The role of interleukin-2 during homeostasis and activation of the immune system
Onur Boyman et al.
NATURE REVIEWS IMMUNOLOGY (2012)
Quantitative events determine the differentiation and function of helper T cells
Anne O'Garra et al.
NATURE IMMUNOLOGY (2011)
Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages
Wei Liao et al.
NATURE IMMUNOLOGY (2011)
Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number
Juan Quiel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis
Alice McNally et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Information Transduction Capacity of Noisy Biochemical Signaling Networks
Raymond Cheong et al.
SCIENCE (2011)
Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo
Vandana Kalia et al.
IMMUNITY (2010)
Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells
Matthew E. Pipkin et al.
IMMUNITY (2010)
Only signaling modules that discriminate sharply between stimulatory and nonstimulatory inputs require basal signaling for fast cellular responses
Mykyta Artomov et al.
JOURNAL OF CHEMICAL PHYSICS (2010)
Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response
Ofer Feinerman et al.
MOLECULAR SYSTEMS BIOLOGY (2010)
Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection
Andrej Kosmrlj et al.
NATURE (2010)
Single-cell NF-κB dynamics reveal digital activation and analogue information processing
Savas Tay et al.
NATURE (2010)
CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses
Joshua J. Obar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments
Dorothea Busse et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Maximum entropy models for antibody diversity
Thierry Mora et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Covering a Broad Dynamic Range: Information Processing at the Erythropoietin Receptor
Verena Becker et al.
SCIENCE (2010)
Attenuated T Cell Responses to a High-Potency Ligand In Vivo
Emily Corse et al.
PLOS BIOLOGY (2010)
Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells
Jayajit Das et al.
CELL (2009)
Sequential Polarization and Imprinting of Type 1 T Helper Lymphocytes by Interferon-γ and Interleukin-12
Edda G. Schulz et al.
IMMUNITY (2009)
Antigen Display, T-Cell Activation, and Immune Evasion during Acute and Chronic Ehrlichiosis
Bisweswar Nandi et al.
INFECTION AND IMMUNITY (2009)
Complete but curtailed T-cell response to very low-affinity antigen
Dietmar Zehn et al.
NATURE (2009)
Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression
Dmitry Nevozhay et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
High-Throughput Sequencing of the Zebrafish Antibody Repertoire
Joshua A. Weinstein et al.
SCIENCE (2009)
Recruitment of Antigen-Specific CD8+ T Cells in Response to Infection Is Markedly Efficient
Jeroen W. J. van Heijst et al.
SCIENCE (2009)
Molecular Origin and Functional Consequences of Digital Signaling and Hysteresis During Ras Activation in Lymphocytes
Arup K. Chakraborty et al.
SCIENCE SIGNALING (2009)
Tumor-specific Th17-polarized cells eradicate large established melanoma
Pawel Muranski et al.
BLOOD (2008)
Cytokine-Induced Signaling Networks Prioritize Dynamic Range over Signal Strength
Kevin A. Janes et al.
CELL (2008)
Variability and robustness in T cell activation from regulated heterogeneity in protein levels
Ofer Feinerman et al.
SCIENCE (2008)
Dynamics of Immune Escape during HIV/SIV Infection
Christian L. Althaus et al.
PLOS COMPUTATIONAL BIOLOGY (2008)
Digital NFATc2 Activation per Cell Transforms Graded T Cell Receptor Activation into an All-or-None IL-2 Expression
Miriam Podtschaske et al.
PLOS ONE (2007)
Modeling the mechanisms of acute hepatitis B virus infection
Stanca M. Ciupe et al.
JOURNAL OF THEORETICAL BIOLOGY (2007)
Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections
Martin F. Bachmann et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
Network motifs: theory and experimental approaches
Uri Alon
NATURE REVIEWS GENETICS (2007)
Quantitative network signal combinations downstream of TCR activation can predict IL-2 production response
Melissa L. Kemp et al.
JOURNAL OF IMMUNOLOGY (2007)
Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion
Zacarias Garcia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals
Alejandro V. Villarino et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Cutting edge: Paracrine, but not autocrine, IL-2 signaling is sustained during early antliviiral. CD4 T cell response
Meixiao Long et al.
JOURNAL OF IMMUNOLOGY (2006)
Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells
Matthew A. Williams et al.
NATURE (2006)
Intratumor CD4 T-cell accumulation requires stronger priming than for expansion and lymphokine secretion
Nathalie T. Joncker et al.
CANCER RESEARCH (2006)
Modeling T cell antigen discrimination based on feedback control of digital ERK responses
G Altan-Bonnet et al.
PLOS BIOLOGY (2005)
Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment
H Yamane et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
SUNDIALS: Suite of nonlinear and differential/algebraic equation solvers
AC Hindmarsh et al.
ACM TRANSACTIONS ON MATHEMATICAL SOFTWARE (2005)
Inferring dynamic architecture of cellular networks using time series of gene expression, protein and metabolite data
E Sontag et al.
BIOINFORMATICS (2004)
Constitutive and ligand-induced TCR degradation
M von Essen et al.
JOURNAL OF IMMUNOLOGY (2004)
Compensatory energetic mechanisms mediating the assembly of signaling complexes between interleukin-2 and its α, β, and γc receptors
M Rickert et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
IL-2 secretion by CD4+ T cells in vivo is rapid, transient, and influenced by TCR-specific competition
DK Sojka et al.
JOURNAL OF IMMUNOLOGY (2004)
Structure and function of the feed-forward loop network motif
S Mangan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Continuous T cell receptor signaling required for synapse maintenance and full effector potential
JB Huppa et al.
NATURE IMMUNOLOGY (2003)
Stochastic model of T cell proliferation: A calculus revealing IL-2 regulation of precursor frequencies, cell cycle time, and survival
EK Deenick et al.
JOURNAL OF IMMUNOLOGY (2003)
Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process
D Bruniquel et al.
NATURE IMMUNOLOGY (2003)
Mechanisms of noise-resistance in genetic oscillators
JMG Vilar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
CD8+ T-cell homeostasis after infection:: setting the 'curve'
VP Badovinac et al.
MICROBES AND INFECTION (2002)
T cells down-modulate peptide-MHC complexes on APCs in vivo
RM Kedl et al.
NATURE IMMUNOLOGY (2002)
Antigen decoding by T lymphocytes: from synapses to fate determination
A Lanzavecchia et al.
NATURE IMMUNOLOGY (2001)
Visualizing T cell competition for peptide/MHC complexes: A specific mechanism to minimize the effect of precursor frequency
A Smith et al.
IMMUNITY (2000)