Related references
Note: Only part of the references are listed.Interaction Domains of Sos1/Grb2 Are Finely Tuned for Cooperative Control of Embryonic Stem Cell Fate
Greg M. Findlay et al.
CELL (2013)
REGULATION OF SMALL GTPases BY GEFs, GAPs, AND GDIs
Jacqueline Cherfils et al.
PHYSIOLOGICAL REVIEWS (2013)
RasGRP1, but Not RasGRP3, Is Required for Efficient Thymic β-Selection and ERK Activation Downstream of CXCR4
Dominic P. Golec et al.
PLOS ONE (2013)
Dysregulated RasGRP1 Responds to Cytokine Receptor Input in T Cell Leukemogenesis
Catherine Hartzell et al.
SCIENCE SIGNALING (2013)
The Role of Ras Guanine Nucleotide Releasing Protein 4 in FcεRI-mediated Signaling, Mast Cell Function, and T Cell Development
Minghua Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Deconstructing Ras Signaling in the Thymus
Robert L. Kortum et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Aberrant expression of RasGRP1 cooperates with gain-of-function NOTCH1 mutations in T-cell leukemogenesis
T. Oki et al.
LEUKEMIA (2012)
Regulating the regulator: post-translational modification of RAS
Ian M. Ahearn et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Regulation of RasGRP1 Function in T Cell Development and Activation by Its Unique Tail Domain
Deirdre M. Fuller et al.
PLOS ONE (2012)
Overview of the CCP4 suite and current developments
Martyn D. Winn et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2011)
Crystal Structure and Allosteric Activation of Protein Kinase C βII
Thomas A. Leonard et al.
CELL (2011)
Phosphoinositide 3-Kinase Regulates Plasma Membrane Targeting of the Ras-specific Exchange Factor RasGRP1
Bari Zahedi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Three-dimensional triple-resonance NMR Spectroscopy of isotopically enriched proteins
Lewis E. Kay et al.
JOURNAL OF MAGNETIC RESONANCE (2011)
STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development
Andre Limnander et al.
NATURE IMMUNOLOGY (2011)
RasGRP3, a Ras activator, contributes to signaling and the tumorigenic phenotype in human melanoma
D. Yang et al.
ONCOGENE (2011)
Targeted Sos1 deletion reveals its critical role in early T-cell development
Robert L. Kortum et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases
Vincent Plagnol et al.
PLOS GENETICS (2011)
XDS
Wolfgang Kabsch
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
RasGRP3 Contributes to Formation and Maintenance of the Prostate Cancer Phenotype
Dazhi Yang et al.
CANCER RESEARCH (2010)
MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1
Wen Pan et al.
JOURNAL OF IMMUNOLOGY (2010)
Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity
Edward T. Petri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless
Jodi Gureasko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Taxonomy and function of C1 protein kinase C homology domains
James H. Hurley et al.
PROTEIN SCIENCE (2010)
Cytosolic Ca2+ Buffers
Beat Schwaller
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
Averaged kick maps: less noise, more signal...and probably less bias
Jure Praznikar et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2009)
RasGRP1 Transgenic Mice Develop Cutaneous Squamous Cell Carcinomas in Response to Skin Wounding Potential Role of Granulocyte Colony-Stimulating Factor
Federico R. Diez et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Membrane localization of RasGRP1 is controlled by an EF-hand, and by the GEF domain
Ghazaleh Tazmini et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells
Jayajit Das et al.
CELL (2009)
TALOS plus : a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts
Yang Shen et al.
JOURNAL OF BIOMOLECULAR NMR (2009)
Association of RASGRP1 with type 1 diabetes is revealed by combined follow-up of two genome-wide studies
H. Q. Qu et al.
JOURNAL OF MEDICAL GENETICS (2009)
Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras
Jennifer O. Lauchle et al.
NATURE (2009)
Origin of the sharp boundary that discriminates positive and negative selection of thymocytes
Ashok Prasad et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Regulatory and structural EF-hand motifs of neuronal calcium sensor-1:: Mg2+ modulates Ca2+ binding, Ca2+-induced conformational changes, and equilibrium unfolding transitions
Penmatsa Aravind et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B
Holger Rehmann et al.
NATURE (2008)
Membrane-dependent signal integration by the Ras activator Son of sevenless
Jodi Gureasko et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Structural basis and mechanism of autoregulation in 3-phosphoinositide-dependent Grp1 family Arf GTPase exchange factors
Jonathan P. DiNitto et al.
MOLECULAR CELL (2007)
RasGRP1 overexpression in the epidermis of Transgenic mice contributes to tumor progression during multistage skin carcinogenesis
Courtney T. Luke et al.
CANCER RESEARCH (2007)
Defective expression of ras guanyl nucleotide-releasing protein 1 in a subset of patients with systemic lupus erythematosus
Shinsuke Yasuda et al.
JOURNAL OF IMMUNOLOGY (2007)
Regulation of RasGRP1 by B cell antigen receptor requires cooperativity between three domains controlling translocation to the plasma membrane
Nadine Beaulieu et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Ras oncogenes and their downstream targets
Krishnaraj Rajalingam et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)
Phaser crystallographic software
Airlie J. McCoy et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)
Structures and metal-ion-binding properties of the Ca2+-binding helix-loop-helix EF-hand motifs
Jessica L. Gifford et al.
BIOCHEMICAL JOURNAL (2007)
GEFs and GAPs: Critical elements in the control of small G proteins
Johannes L. Bos et al.
CELL (2007)
Evaluating protein structures determined by structural genomics consortia
Aneerban Bhattacharya et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)
Version 1.2 of the Crystallography and NMR system
Axel T. Brunger
NATURE PROTOCOLS (2007)
Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome
Marco Tartaglia et al.
NATURE GENETICS (2007)
Germline gain-of-function mutations in SOS1 cause Noonan syndrome
Amy E. Roberts et al.
NATURE GENETICS (2007)
Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes
Jeroen P. Roose et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Transgenic overexpression of RasGRP1 in mouse epidermis results in spontaneous tumors of the skin
Carolyn E. Oki-Idouchi et al.
CANCER RESEARCH (2007)
Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling
Mark A. Daniels et al.
NATURE (2006)
Regulation of Ras signaling dynamics by Sos-mediated positive feedback
Sean Boykevisch et al.
CURRENT BIOLOGY (2006)
A Ras-induced conformational switch in the Ras activator Son of sevenless
Tanya S. Freedman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
PREDITOR: a web server for predicting protein torsion angle restraints
Mark V. Berjanskii et al.
NUCLEIC ACIDS RESEARCH (2006)
Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling
PO Krutzik et al.
NATURE METHODS (2006)
Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state
H Rehmann et al.
NATURE (2006)
RasGRP1 and RasGRP3 regulate B cell proliferation by facilitating B cell receptor-Ras signaling
JJ Coughlin et al.
JOURNAL OF IMMUNOLOGY (2005)
A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells
JP Roose et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Deregulated expression of RasGRP1 initiates thymic lymphomagenesis independently of T-cell receptors
MB Klinger et al.
ONCOGENE (2005)
PKCδ associates with and is involved in the phosphorylation of RasGRP3 in response to phorbol esters
C Brodie et al.
MOLECULAR PHARMACOLOGY (2004)
Activation of RasGRP3 by phosphorylation of Thr-133 is required ifor B cell receptor-mediated Ras activation
Y Aiba et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
RTCGD: retroviral tagged cancer gene database
K Akagi et al.
NUCLEIC ACIDS RESEARCH (2004)
Structural mechanism for lipid activation of the Rac-specific GAP, β2-chimaerin
B Canagarajah et al.
CELL (2004)
Structural analysis of autoinhibition in the Ras activator son of sevenless
H Sondermann et al.
CELL (2004)
Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1
K Layer et al.
IMMUNITY (2003)
Rational design of a calcium-binding protein
W Yang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Structural evidence for feedback activation by Ras-GTP of the Ras-specific nucleotide exchange factor SOS
SM Margarit et al.
CELL (2003)
Engineering new metal specificity in EF-hand peptides
L Le Clainche et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2003)
New genes involved in cancer identified by retroviral tagging
T Suzuki et al.
NATURE GENETICS (2002)
High-throughput retroviral tagging to identify components of specific signaling pathways in cancer
H Mikkers et al.
NATURE GENETICS (2002)
RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia
GW Reuther et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Structural independence of the two EF-hand domains of caltractin
S Veeraraghavan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs - Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function
Y Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Signal transduction - The guanine nucleotide-binding switch in three dimensions
IR Vetter et al.
SCIENCE (2001)
Structure-based mutagenesis reveals distinct functions for Ras switch 1 and switch 2 in Sos-catalyzed guanine nucleotide exchange
BE Hall et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
RasGRP essential for mouse thymocyte differentiation and TCR signaling
NA Dower et al.
NATURE IMMUNOLOGY (2000)
Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor
CL Day et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Prediction of sterically induced alignment in a dilute liquid crystalline phase: Aid to protein structure determination by NMR
M Zweckstetter et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)
Share Paper
