Related references
Note: Only part of the references are listed.Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathways
Hiroyasu Ogawa et al.
GENES & DEVELOPMENT (2014)
High resistance of the mechanical properties of the chondrocyte pericellular matrix to proteoglycan digestion by chondroitinase, aggrecanase, or hyaluronidase
Rebecca E. Wilusz et al.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS (2014)
Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes
C. L. Thompson et al.
OSTEOARTHRITIS AND CARTILAGE (2014)
Periodic Mechanical Stress Stimulates the FAK Mitogenic Signal in Rat Chondrocytes Through ERK1/2 Activity
Wenwei Liang et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2013)
Targeting mechanotransduction pathways in osteoarthritis: a focus on the pericellular matrix
Tonia L. Vincent
CURRENT OPINION IN PHARMACOLOGY (2013)
Diurnal variations in articular cartilage thickness and strain in the human knee
Jeremy L. Coleman et al.
JOURNAL OF BIOMECHANICS (2013)
Depth-dependent anisotropy of the micromechanical properties of the extracellular and pericellular matrices of articular cartilage evaluated via atomic force microscopy
Morgan A. McLeod et al.
JOURNAL OF BIOMECHANICS (2013)
Changes in chondrocyte gene expression following in vitro impaction of porcine articular cartilage in an impact injury model
Melissa S. Ashwell et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2013)
Effects of cartilage impact with and without fracture on chondrocyte viability and the release of inflammatory markers
Josef A. Stolberg-Stolberg et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2013)
Replication of chronic abnormal cartilage loading by medial meniscus destabilization for modeling osteoarthritis in the rabbit knee in vivo
Marut Arunakul et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2013)
Synovial fluid concentrations and relative potency of interleukin-1 alpha and beta in cartilage and meniscus degradation
Amy L. McNulty et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2013)
Micromechanical mapping of early osteoarthritic changes in the pericellular matrix of human articular cartilage
R. E. Wilusz et al.
OSTEOARTHRITIS AND CARTILAGE (2013)
Histone deacetylase inhibitors suppress mechanical stress-induced expression of RUNX-2 and ADAMTS-5 through the inhibition of the MAPK signaling pathway in cultured human chondrocytes
T. Saito et al.
OSTEOARTHRITIS AND CARTILAGE (2013)
Stress-Induced Cartilage Degradation Does Not Depend on the NLRP3 Inflammasome in Human Osteoarthritis and Mouse Models
Carole Bougault et al.
ARTHRITIS AND RHEUMATISM (2012)
Osteoarthritis: A disease of the joint as an organ
Richard F. Loeser et al.
ARTHRITIS AND RHEUMATISM (2012)
Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo
Annika Burleigh et al.
ARTHRITIS AND RHEUMATISM (2012)
Primary cilia mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes
Angus K. T. Wann et al.
FASEB JOURNAL (2012)
Immunofluorescence-guided atomic force microscopy to measure the micromechanical properties of the pericellular matrix of porcine articular cartilage
Rebecca E. Wilusz et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2012)
ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation
Jessica L. Allen et al.
MOLECULAR BIOLOGY OF THE CELL (2012)
A biomechanical role for perlecan in the pericellular matrix of articular cartilage
Rebecca E. Wilusz et al.
MATRIX BIOLOGY (2012)
Depletion of primary cilia in articular chondrocytes results in reduced Gli3 repressor to activator ratio, increased Hedgehog signaling, and symptoms of early osteoarthritis
C. -F Chang et al.
OSTEOARTHRITIS AND CARTILAGE (2012)
Dynamic Compression of Chondrocyte-Agarose Constructs Reveals New Candidate Mechanosensitive Genes
Carole Bougault et al.
PLOS ONE (2012)
Biomechanical factors in osteoarthritis
Farshid Guilak
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2011)
Proteinase-activated Receptor-2 Gene Disruption Limits the Effect of Osteoarthritis on Cartilage in Mice: A Novel Target in Joint Degradation
Nathalie Amiable et al.
JOURNAL OF RHEUMATOLOGY (2011)
Subchondral bone changes in three different canine models of osteoarthritis
K. Kuroki et al.
OSTEOARTHRITIS AND CARTILAGE (2011)
Mechanical Loading of Articular Cartilage Reduces IL-I-Induced Enzyme Expression
P. A. Torzilli et al.
CARTILAGE (2011)
Chondroprotective Role of the Osmotically Sensitive Ion Channel Transient Receptor Potential Vanilloid 4 Age- and Sex-Dependent Progression of Osteoarthritis in Trpv4-Deficient Mice
Andrea L. Clark et al.
ARTHRITIS AND RHEUMATISM (2010)
Spatial Mapping of the Biomechanical Properties of the Pericellular Matrix of Articular Cartilage Measured In Situ via Atomic Force Microscopy
Eric M. Darling et al.
BIOPHYSICAL JOURNAL (2010)
An Axisymmetric Boundary Element Model for Determination of Articular Cartilage Pericellular Matrix Properties In Situ via Inverse Analysis of Chondron Deformation
Eunjung Kim et al.
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME (2010)
In vivo tibiofemoral cartilage deformation during the stance phase of gait
Fang Liu et al.
JOURNAL OF BIOMECHANICS (2010)
In vivo cartilage contact strains in patients with lateral ankle instability
Johanna E. Bischof et al.
JOURNAL OF BIOMECHANICS (2010)
αv and β1 integrins regulate dynamic compression-induced proteoglycan synthesis in 3D gel culture by distinct complementary pathways
D. H. Chai et al.
OSTEOARTHRITIS AND CARTILAGE (2010)
Mechanical load inhibits IL-1 induced matrix degradation in articular cartilage
P. A. Torzilli et al.
OSTEOARTHRITIS AND CARTILAGE (2010)
Mechanical signals control SOX-9, VEGF, and c-Myc expression and cell proliferation during inflammation via integrin-linked kinase, B-Raf, and ERK1/2-dependent signaling in articular chondrocytes
Priyangi M. Perera et al.
ARTHRITIS RESEARCH & THERAPY (2010)
Increased Tibiofemoral Cartilage Contact Deformation in Patients With Anterior Cruciate Ligament Deficiency
Samuel K. Van de Velde et al.
ARTHRITIS AND RHEUMATISM (2009)
Functional Characterization of TRPV4 as an Osmotically Sensitive Ion Channel in Porcine Articular Chondrocytes
Mimi N. Phan et al.
ARTHRITIS AND RHEUMATISM (2009)
Developmental and Osteoarthritic Changes in Col6a1-Knockout Mice Biomechanics of Type VI Collagen in the Cartilage Pericellular Matrix
Leonidas G. Alexopoulos et al.
ARTHRITIS AND RHEUMATISM (2009)
Matrix Metalloproteinase 13-Deficient Mice Are Resistant to Osteoarthritic Cartilage Erosion but Not Chondrocyte Hypertrophy or Osteophyte Development
C. B. Little et al.
ARTHRITIS AND RHEUMATISM (2009)
Duty Cycle of Deformational Loading Influences the Growth of Engineered Articular Cartilage
Kenneth W. Ng et al.
CELLULAR AND MOLECULAR BIOENGINEERING (2009)
Biomechanical Thresholds Regulate Inflammation through the NF-κB Pathway: Experiments and Modeling
Jin Nam et al.
PLOS ONE (2009)
Temporal effects of impact on articular cartilage cell death, gene expression, matrix biochemistry, and biomechanics
Roman M. Natoli et al.
ANNALS OF BIOMEDICAL ENGINEERING (2008)
Signal transduction pathways involving p38 MAPK, JNK, NFκB and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1β and dynamic compression
T. T. Chowdhury et al.
INFLAMMATION RESEARCH (2008)
Synergistic and Additive Effects of Hydrostatic Pressure and Growth Factors on Tissue Formation
Benjamin D. Elder et al.
PLOS ONE (2008)
Effect of physical activity on articular knee joint structures in community-based adults
Tina L. Racunica et al.
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH (2007)
The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129/SvEv mouse
S. S. Glasson et al.
OSTEOARTHRITIS AND CARTILAGE (2007)
Zonal changes in the three-dimensional morphology of the chondron under compression: The relationship among cellular, pericellular, and extracellular deformation in articular cartilage
Jae Bong Choi et al.
JOURNAL OF BIOMECHANICS (2007)
Analysis of the relationship between peak stress and proteoglycan loss following injurious compression of human post-mortem knee and ankle cartilage
Parth Patwari et al.
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY (2007)
A mechano-chemical model for the passive swelling response of an isolated chondron under osmotic loading
MA Haider et al.
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY (2006)
Integrin-mediated mechanotransduction in IL-1β stimulated chondrocytes
T. T. Chowdhury et al.
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY (2006)
The effects of exercise on human articular cartilage
F Eckstein et al.
JOURNAL OF ANATOMY (2006)
Osteoarthritis: Epidemiology
N Arden et al.
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2006)
Indentation testing of human articular cartilage: Effects of probe tip geometry and indentation depth on intra-tissue strain
WC Bae et al.
JOURNAL OF BIOMECHANICS (2006)
Gene expression profile of mechanically impacted bovine articular cartilage explants
PS Chan et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2005)
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
SS Glasson et al.
NATURE (2005)
Change in knee cartilage T2 at MR imaging after running: A feasibility study
TJ Mosher et al.
RADIOLOGY (2005)
Ultrastructural quantification of cell death after injurious compression of bovine calf articular cartilage
P Patwari et al.
OSTEOARTHRITIS AND CARTILAGE (2004)
Integrin-dependent signal cascades in chondrocyte mechanotransduction
SJ Millward-Sadler et al.
ANNALS OF BIOMEDICAL ENGINEERING (2004)
Basic fibroblast growth factor mediates transduction of mechanical signals when articular cartilage is loaded
TL Vincent et al.
ARTHRITIS AND RHEUMATISM (2004)
Influence of tissue maturation and antioxidants on the apoptotic response of articular cartilage after injurious compression
B Kurz et al.
ARTHRITIS AND RHEUMATISM (2004)
Increased stromelysin-1 (MMP-3), proteoglycan degradation (3B3-and 7D4) and collagen damage in cyclically load-injured articular cartilage
PM Lin et al.
OSTEOARTHRITIS AND CARTILAGE (2004)
The role of biomechanics and inflammation in cartilage injury and repair
F Guilak et al.
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (2004)
Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP
JB Fitzgerald et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Synergistic action of growth factors and dynamic loading for articular cartilage tissue engineering
RL Mauck et al.
TISSUE ENGINEERING (2003)
Proteoglycan degradation after injurious compression of bovine and human articular cartilage in vitro
P Patwari et al.
ARTHRITIS AND RHEUMATISM (2003)
A comparison of joint stability between anterior cruciate intact and deficient knees: a new canine model of anterior cruciate ligament disruption
MJ Lopez et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2003)
Cytokine production in the infrapatellar fat pad: another source of cytokines in knee synovial fluids
T Ushiyama et al.
ANNALS OF THE RHEUMATIC DISEASES (2003)
Induction of cyclooxygenase-2 by mechanical stress through a nitric oxide-regulated pathway
B Fermor et al.
OSTEOARTHRITIS AND CARTILAGE (2002)
Biosynthetic response and mechanical properties of articular cartilage after injurious compression
B Kurz et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2001)
Dynamic compression inhibits the synthesis of nitric oxide and PGE2 by IL-1β-stimulated chondrocytes cultured in agarose constructs
TT Chowdhury et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Depth- and strain-dependent mechanical and electromechanical properties of full-thickness bovine articular cartilage in confined compression
AC Chen et al.
JOURNAL OF BIOMECHANICS (2001)
The effect of dynamic compression on the response of articular cartilage to insulin-like growth factor-I
LJ Bonassar et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2001)
The mechanical environment of the chondrocyte: a biphasic finite element model of cell-matrix interactions in articular cartilage
F Guilak et al.
JOURNAL OF BIOMECHANICS (2000)
Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis
AM Loening et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
Cyclic tensile strain acts as an antagonist of IL-1β actions in chondrocytes
ZF Xu et al.
JOURNAL OF IMMUNOLOGY (2000)
Mechanical and physicochemical regulation of the action of insulin-like growth factor-I on articular cartilage
LJ Bonassar et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels
RL Mauck et al.
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME (2000)