Journal
BIOMED RESEARCH INTERNATIONAL
Volume 2014, Issue -, Pages -Publisher
HINDAWI LTD
DOI: 10.1155/2014/436097
Keywords
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Funding
- National Natural Science Foundation [31260609, 31201900]
- Gansu Natural Science Foundation [1308RJZA105]
- Science Fund for Creative Research Groups of Gansu Province [1210RJIA006]
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NF-kappa B signaling network is a crucial component of innate immunity. miRNAs are a subtype of small noncoding RNAs, involved in regulation of gene expression at the posttranscriptional level. Increasing evidence has emerged that miRNAs play an important role in regulation of NF-kappa B signaling pathway during viral infections. Both host and viral miRNAs are attributed to modulation of NF-kappa B activity, thus affecting viral infection and clearance. Understandings of the mechanisms of these miRNAs will open a direction for development of novel antivirus drugs.
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