Related references
Note: Only part of the references are listed.The multiple, complex roles of versican and its proteolytic turnover by ADAMTS proteases during embryogenesis
Sumeda Nandadasa et al.
MATRIX BIOLOGY (2014)
Biosynthesis and Expression of a Disintegrin-like and Metalloproteinase Domain with Thrombospondin-1 Repeats-15 A NOVEL VERSICAN-CLEAVING PROTEOGLYCANASE
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JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valves
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JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
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NEUROSCIENCE (2013)
ADAMTS1, ADAMTS5, ADAMTS9 and aggrecanase-generated proteoglycan fragments are induced following spinal cord injury in mouse
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NEUROSCIENCE LETTERS (2013)
The endogenous proteoglycan-degrading enzyme ADAMTS-4 promotes functional recovery after spinal cord injury
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JOURNAL OF NEUROINFLAMMATION (2012)
Selective Decline of Synaptic Protein Levels in the Frontal Cortex of Female Mice Deficient in the Extracellular Metalloproteinase ADAMTS1
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PLOS ONE (2012)
Altered versican cleavage in ADAMTS5 deficient mice; A novel etiology of myxomatous valve disease
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DEVELOPMENTAL BIOLOGY (2011)
Emerging roles for ADAMTS5 during development and disease
Christopher Kintakas et al.
MATRIX BIOLOGY (2011)
Extracellular Protease ADAMTS9 Suppresses Esophageal and Nasopharyngeal Carcinoma Tumor Formation by Inhibiting Angiogenesis
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CANCER RESEARCH (2010)
Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation
Hiroyuki Enomoto et al.
DEVELOPMENT (2010)
ADAMTS Metalloproteases Generate Active Versican Fragments that Regulate Interdigital Web Regression
Daniel R. McCulloch et al.
DEVELOPMENTAL CELL (2009)
Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues
Daniel R. McCulloch et al.
GENE EXPRESSION PATTERNS (2009)
Evidence of a novel aggrecan-degrading activity in cartilage - Studies of mice deficient in both ADAMTS-4 and ADAMTS-5
Fraser M. Rogerson et al.
ARTHRITIS AND RHEUMATISM (2008)
Multimodal signaling by the ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) promotes neurite extension
Michelle G. Hamel et al.
EXPERIMENTAL NEUROLOGY (2008)
The secreted metalloprotease ADAMTS20 is required for melanoblast survival
Debra L. Silver et al.
PLOS GENETICS (2008)
Distinguishing aggrecan loss from aggrecan proteolysis in ADAMTS-4 and ADAMTS-5 single and double deficient mice
Mirna Z. Ilic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis
Manas K. Majumdar et al.
ARTHRITIS AND RHEUMATISM (2007)
ADAMTS-like 2 (ADAMTSL2) is a secreted glycoprotein that is widely expressed during mouse embryogenesis and is regulated during skeletal myogenesis
Bon-Hun Koo et al.
MATRIX BIOLOGY (2007)
ADAMTS-5 deficiency does not block aggrecanolysis at preferred cleavage sites in the chondroitin sulfate-rich region of aggrecan
Charlotte J. East et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The quantification of ADAMTS expression in an animal model of cerebral ischemia using real-time PCR
Y. F. Tian et al.
ACTA ANAESTHESIOLOGICA SCANDINAVICA (2007)
Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5
Ruo-Hua Song et al.
ARTHRITIS AND RHEUMATISM (2007)
Requirement for ADAMTS-1 in extracellular matrix remodeling during ovarian folliculogenesis and lymphangiogenesis
Hannah M. Brown et al.
DEVELOPMENTAL BIOLOGY (2006)
Cell-surface processing of pro-ADAMTS9 by furin
BH Koo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively
YJ Liu et al.
ONCOGENE (2006)
Human glioblastomas overexpress ADAMTS-5 that degrades brevican
M Nakada et al.
ACTA NEUROPATHOLOGICA (2005)
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
SS Glasson et al.
NATURE (2005)
ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
H Stanton et al.
NATURE (2005)
ADAMTS4 (aggrecanase-1) cleaves human brain versican V2 at Glu405-Gln406 to generate glial hyaluronate binding protein
J Westling et al.
BIOCHEMICAL JOURNAL (2004)
ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage
LA Collins-Racie et al.
MATRIX BIOLOGY (2004)
Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage
AM Malfait et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
ADAMTS4 cleaves at the aggrecanase site (Glu373-Ala374) and secondarily at the matrix metalloproteinase site (Asn341-Phe342) in the aggrecan interglobular domain
J Westling et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Association between protease-specific proteolytic cleavage of brevican and synaptic loss in the dentate gyrus of kainate-treated rats
W Yuan et al.
NEUROSCIENCE (2002)
Brevican is degraded by matrix metalloproteinases and aggrecanase-1 (ADAMTS4) at different sites
H Nakamura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
ADAMTS-4 (a disintegrin and metalloproteinase with thrombospondin motifs) is transcriptionally induced in beta-amyloid treated rat astrocytes
K Satoh et al.
NEUROSCIENCE LETTERS (2000)
ADAMTS-1 cleaves a cartilage proteoglycan, aggrecan
K Kuno et al.
FEBS LETTERS (2000)