Journal
BIOMED RESEARCH INTERNATIONAL
Volume 2014, Issue -, Pages -Publisher
HINDAWI LTD
DOI: 10.1155/2014/901428
Keywords
-
Funding
- Natural Science Foundation for Colleges and Universities in Jiangsu Province [13KJB180021]
- Natural Science Foundation of USTS [XKQ201315]
- National Natural Science Foundation of China [31170795, 91230117]
- International SAMP
- T Cooperation Program of Suzhou [SH201120]
- National High Technology Research and Development Program of China (863 Program) [2012AA02A601]
Ask authors/readers for more resources
Gastric cancers (GC) have the high morbidity and mortality rates worldwide and there is a need to identify sufficiently sensitive biomarkers for GC. MicroRNAs (miRNAs) could be promising potential biomarkers for GC diagnosis. We employed a systematic and integrative bioinformatics framework to identify GC-related microRNAs from the public microRNA and mRNA expression dataset generated by RNA-seq technology. The performance of the 17 candidate miRNAs was evaluated by hierarchal clustering, ROC analysis, and literature mining. Fourteen have been found to be associated with GC and three microRNAs (miR-211, let-7b, and miR-708) were for the first time reported to associate with GC and may be used for diagnostic biomarkers for GC.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available