Journal
BIOMED RESEARCH INTERNATIONAL
Volume 2014, Issue -, Pages -Publisher
HINDAWI LTD
DOI: 10.1155/2014/818107
Keywords
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Funding
- Associazione La Nostra Famiglia Fondo DMD Gli Amici di Emanuele
- Associazione Amici del Centro Dino Ferrari
- EU [223098]
- Ministry of Health [RF-2009-1547384]
- Ystem s.r.l.
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Muscular dystrophies (MDs) are a heterogeneous group of diseases, caused by mutations in different components of sarcolemma, extracellular matrix, or enzymes. Inflammation and innate or adaptive immune response activation are prominent features of MDs. Various therapies under development are directed toward rescuing the dystrophicmuscle damage using gene transfer or cell therapy. Here we discussed current knowledge about involvement of immune system responses to experimental therapies in MDs.
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