4.5 Article

Current nanotechnological approaches for an effective delivery of bio-active drug molecules in the treatment of acne

Journal

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
Volume 44, Issue 1, Pages 98-105

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.3109/21691401.2014.916715

Keywords

acne vulgaris; fullerenes; liposomes; micro-sponge; Propionibacterium acnes

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Acne is a chronic inflammatory human skin disease, characterized by areas of skin with seborrhoea, comedones, papules, nodules, pimples, and possibly scarring with lesions occurring on face, neck, and back. Nanotechnological approaches such as particulate (solid lipid nanoparticles and microspheres), vesicular (liposomes and niosomes), colloidal drug delivery systems (micro-emulsion and nano-emulsion), and miscellaneous systems (aerosol foams and micro-sponges) have an important place in acne therapy. These approaches have an enormous opportunity for the designing of a novel, low-dose and effective treatment systems to control acne disease. In this review, we specially focus on the different nanotechnological approaches for an effective treatment of acne.

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