4.5 Article

Ceramic nanoparticles: Recompense, cellular uptake and toxicity concerns

Journal

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
Volume 44, Issue 1, Pages 401-409

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.3109/21691401.2014.955106

Keywords

ceramic nanocarriers; cellular uptake; nanoparticles; nanosystems; toxicity

Funding

  1. DST-FIST
  2. [UGC-MRP-41-748-2012]
  3. [UGC-RA 70-371/2012]

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Over the past few years, nanoparticles and their role in drug delivery have been the centre of attraction as new drug delivery systems. Various forms of nanosystems have been designed, such as nanoclays, scaffolds and nanotubes, having numerous applications in areas such as drug loading, target cell uptake, bioassay and imaging. The present study discusses various types of nanoparticles, with special emphasis on ceramic nanocarriers. Ceramic materials have high mechanical strength, good body response and low or non-existing biodegradability. In this article, the various aspects concerning ceramic nanoparticles, such as their advantages over other systems, their cellular uptake and toxicity concerns are discussed in detail.

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