4.7 Review

Current Understanding on Aflatoxin Biosynthesis and Future Perspective in Reducing Aflatoxin Contamination

Journal

TOXINS
Volume 4, Issue 11, Pages 1024-1057

Publisher

MDPI
DOI: 10.3390/toxins4111024

Keywords

aflatoxins; mycotoxins; Aspergillus flavus; gene cluster; gene regulation; biocontrol; food contaminants

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Traditional molecular techniques have been used in research in discovering the genes and enzymes that are involved in aflatoxin formation and genetic regulation. We cloned most, if not all, of the aflatoxin pathway genes. A consensus gene cluster for aflatoxin biosynthesis was discovered in 2005. The factors that affect aflatoxin formation have been studied. In this report, the author summarized the current status of research progress and future possibilities that may be used for solving aflatoxin contamination.

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