4.7 Review

Trichothecenes: From Simple to Complex Mycotoxins

Journal

TOXINS
Volume 3, Issue 7, Pages 802-814

Publisher

MDPI AG
DOI: 10.3390/toxins3070802

Keywords

trichothecenes; mycotoxins; Type A; Type B; macrocyclic; d-type; t-type; toxin biosynthesis

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As the world's population grows, access to a safe food supply will continue to be a global priority. In recent years, the world has experienced an increase in mycotoxin contamination of grains due to climatic and agronomic changes that encourage fungal growth during cultivation. A number of the molds that are plant pathogens produce trichothecene mycotoxins, which are known to cause serious human and animal toxicoses. This review covers the types of trichothecenes, their complexity, and proposed biosynthetic pathways of trichothecenes.

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