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Concise Review: Personalized Human Bone Grafts for Reconstructing Head and Face

Journal

STEM CELLS TRANSLATIONAL MEDICINE
Volume 1, Issue 1, Pages 64-69

Publisher

ALPHAMED PRESS
DOI: 10.5966/sctm.2011-0020

Keywords

Stem cell; Tissue regeneration; Bone; Bone marrow stromal cells; Cellular therapy

Funding

  1. NIH [DE161525, EB02520]
  2. New York Stem Cell Foundation [CU09-3055]

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Regeneration of normal shape, architecture, and function of craniofacial tissues following congenital abnormality, trauma, or surgical treatment presents special problems to tissue engineering. Because of the great variations in properties of these tissues, currently available treatment options fall short of adequate care. We propose that the engineering of personalized bone graft customized to the patient and the specific clinical condition would revolutionize the way we currently treat craniofacial defects and discuss some of the current and emerging treatment modalities. STEM CELLS TRANSLATIONAL MEDICINE 2012;1:64-69

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