Journal
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY
Volume 9, Issue 2, Pages 229-239Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/1756283X15607414
Keywords
bacteriotherapy; Clostridium difficile infection; fecal microbiota transplantation; gut microbiome; inflammatory bowel disease
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Funding
- NIAID NIH HHS [R21 AI121575] Funding Source: Medline
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There has been increasing interest in understanding the role of the human gut microbiome to elucidate the therapeutic potential of its manipulation. Fecal microbiota transplantation (FMT) is the administration of a solution of fecal matter from a donor into the intestinal tract of a recipient in order to directly change the recipient's gut microbial composition and confer a health benefit. FMT has been used to successfully treat recurrent Clostridium difficile infection. There are preliminary indications to suggest that it may also carry therapeutic potential for other conditions such as inflammatory bowel disease, obesity, metabolic syndrome, and functional gastrointestinal disorders.
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