Journal
REVISTA BRASILEIRA DE REUMATOLOGIA
Volume 52, Issue 4, Pages 645-650Publisher
ELSEVIER SCIENCE INC
DOI: 10.1590/S0482-50042012000400014
Keywords
rheumatoid arthritis; ulcerative colitis; spondyloarthritis
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Ulcerative colitis is an autoimmune disorder of unknown etiology. Although the large intestine is the major focus of autoimmunity, resulting in chronic diarrhea, that is actually a systemic disease, with numerous extraintestinal manifestations, such as articular involvement. The frequent association of a number of autoimmune diseases in the same patient has been described. However, the coexistence of ulcerative colitis and rheumatoid arthritis is rare. The authors report a case of ulcerative colitis associated with rheumatoid arthritis, in which colitis occurred 12 years before the onset of inflammatory arthropathy.
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