4.2 Article

Diagnostic accuracy of the Finnish Diabetes Risk Chock for Score (FINDRISC) for undiagnosed T2DM in Peruvian population

Journal

PRIMARY CARE DIABETES
Volume 12, Issue 6, Pages 517-525

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.pcd.2018.07.015

Keywords

Diabetes mellitus, type 2; Glucose tolerance test; Risk assessment; Screening; Diagnostic test

Funding

  1. Wellcome Trust, London, UK [103994/Z/14/Z, 098504/Z/12M]

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Aims: To assess the diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM and to compare its performance with the Latin-American FINDRISC (LA-FINDRISC) and the Peruvian Risk Score. Materials and methods: A population-based study was conducted. T2DM and undiagnosed T2DM were defined using oral glucose tolerance test (OGTT). Risk scores assessed were FINDRISC, LA-FINDRISC and Peruvian Risk Score. Diagnostic accuracy of risk scores was estimated using the c-statistic and the area under the ROC curve (aROC). A simplified version of FINDRISC was also derived. Results: Data from 1609 individuals, mean age 48.2 (SD: 10.6), 810 (50.3%) women, were collected. A total of 176 (11.0%; 95%CI: 9.4%-12.5%) were classified as having T2DM, and 71 (4.7%; 95%CI: 3.7%-5.8%) were classified as having undiagnosed T2DM. Diagnostic accuracy of the FINDRISC (aROC =0.69), LA-FINDRISC (aROC = 0.68), and Peruvian Risk Score (aROC = 0.64) was similar (p=0.15). The simplified FINDRISC, with 4 variables, had a slightly better performance (aROC =0.71) than the other scores. Conclusion: The performance of FINDRISC, LA-FINDRISC and Peruvian Risk Score for undiagnosed T2DM was similar. A simplified FINDRISC can perform as well or better for undiagnosed T2DM. The FINDRISC may be useful to detect cases of undiagnosed T2DM in resource-constrained settings. (C) 2018 The Author(s). Published by Elsevier Ltd on behalf of Primary Care Diabetes Europe.

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