4.7 Review

Thermoresponsive Polymers for Biomedical Applications

Journal

POLYMERS
Volume 3, Issue 3, Pages 1215-1242

Publisher

MDPI
DOI: 10.3390/polym3031215

Keywords

biopolymer; thermoresponsive; stimuli responsive; smart materials; gene delivery; drug delivery; tissue engineering; gels; polymer networks; hydrogels; micelles; nanoparticles; polymersomes

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Thermoresponsive polymers are a class of smart materials that have the ability to respond to a change in temperature; a property that makes them useful materials in a wide range of applications and consequently attracts much scientific interest. This review focuses mainly on the studies published over the last 10 years on the synthesis and use of thermoresponsive polymers for biomedical applications including drug delivery, tissue engineering and gene delivery. A summary of the main applications is given following the different studies on thermoresponsive polymers which are categorized based on their 3-dimensional structure; hydrogels, interpenetrating networks, micelles, crosslinked micelles, polymersomes, films and particles.

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