Journal
PEERJ
Volume 3, Issue -, Pages -Publisher
PEERJ INC
DOI: 10.7717/peerj.1319
Keywords
Metagenomics; Assembly; Genome binning; Visualization; SNP profiling; Metatranscriptomics
Categories
Funding
- G. Unger Vetlesen Foundation
- University of Chicago
- Marine Biological Laboratory
- Medical Research Council [MR/M50161X/1] Funding Source: researchfish
Ask authors/readers for more resources
Advances in high-throughput sequencing and 'omics technologies are revolutionizing studies of naturally occurring microbial communities. Comprehensive investigations of microbial lifestyles require the ability to interactively organize and visualize genetic information and to incorporate subtle differences that enable greater resolution of complex data. Here we introduce anvi'o, an advanced analysis and visualization platform that offers automated and human-guided characterization of microbial genomes in metagenomic assemblies, with interactive interfaces that can link 'omics data from multiple sources into a single, intuitive display. Its extensible visualization approach distills multiple dimensions of information about each contig, offering a dynamic and unified work environment for data exploration, manipulation, and reporting. Using anvi'o, we re-analyzed publicly available datasets and explored temporal genomic changes within naturally occurring microbial populations through de novo characterization of single nucleotide variations, and linked cultivar and single-cell genomes with metagenomic and metatranscriptomic data. Anvi'o is an open-source platform that empowers researchers without extensive bioinformatics skills to performand communicate in-depth analyses on large 'omics datasets.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available