Journal
PM&R
Volume 1, Issue 6, Pages 547-559Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.pmrj.2009.02.013
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Funding
- NICHD NIH HHS [K08 HD001220-04] Funding Source: Medline
- NINDS NIH HHS [R21 NS050135-01A1, R21 NS050135] Funding Source: Medline
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Multipotent cells that can give rise to bone, cartilage, fat, connective tissue, and skeletal and cardiac muscle are termed mesenchymal stem cells. These cells were first identified in the bone marrow, distinct from blood-forming stem cells. Based on the embryologic derivation, availability, and various pro-regenerative characteristics, research exploring their use in cell therapy shows great promise for patients with degenerative muscle diseases and a number of other conditions. In this review, the authors explore the potential for mesenchymal stem cell therapy in the emerging field of regenerative medicine with a focus on treatment for Duchenne muscular dystrophy.
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