Related references
Note: Only part of the references are listed.Fas/CD95 Regulatory Protein Faim2 Is Neuroprotective after Transient Brain Ischemia
Arno Reich et al.
JOURNAL OF NEUROSCIENCE (2011)
Cytoprotective Mitochondrial Chaperone TRAP-1 As a Novel Molecular Target in Localized and Metastatic Prostate Cancer
Irwin Leav et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Mitochondrial dysfunction in Parkinson's disease
Konstanze F. Winklhofer et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1
Frits Kamp et al.
EMBO JOURNAL (2010)
Mitochondrial chaperone tumour necrosis factor receptor-associated protein 1 protects cardiomyocytes from hypoxic injury by regulating mitochondrial permeability transition pore opening
Fei Xiang et al.
FEBS JOURNAL (2010)
The Transgenic Overexpression of α-Synuclein and Not Its Related Pathology Associates with Complex I Inhibition
Virginie Loeb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Parkin Suppresses c-Jun N-Terminal Kinase-Induced Cell Death via Transriptional Regulation in Drosophila
Soojin Hwang et al.
MOLECULES AND CELLS (2010)
TDP-43-Mediated Neuron Loss In Vivo Requires RNA-Binding Activity
Aaron Voigt et al.
PLOS ONE (2010)
Inhibiting α-Synuclein Oligomerization by Stable Cell-Penetrating β-Synuclein Fragments Recovers Phenotype of Parkinson's Disease Model Flies
Ronit Shaltiel-Karyo et al.
PLOS ONE (2010)
Involvement of the mitochondrial apoptotic pathway and nitric oxide synthase in dopaminergic neuronal death induced by 6-hydroxydopamine and lipopolysaccharide
Sarika Singh et al.
REDOX REPORT (2010)
Parkinson's Disease and Residential Exposure to Maneb and Paraquat From Agricultural Applications in the Central Valley of California
Sadie Costello et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2009)
TRAP1, a novel mitochondrial chaperone responsible for multi-drug resistance and protection from apoptotis in human colorectal carcinoma cells
Eleonora Costantino et al.
CANCER LETTERS (2009)
Pre-fibrillar α-synuclein variants with impaired β-structure increase neurotoxicity in Parkinson's disease models
Damla Pinar Karpinar et al.
EMBO JOURNAL (2009)
Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
Vanessa A. Morais et al.
EMBO MOLECULAR MEDICINE (2009)
Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease
Hansruedi Bueeler
EXPERIMENTAL NEUROLOGY (2009)
Parkin deficiency disrupts calcium homeostasis by modulating phospholipase C signalling
Anna Sandebring et al.
FEBS JOURNAL (2009)
Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells
Mordhwaj S. Parihar et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Mitochondrial quality control: insights on how Parkinson's disease related genes PINK1, parkin, and Omi/HtrA2 interact to maintain mitochondrial homeostasis
Ruben K. Dagda et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2009)
Loss of Parkin or PINK1 Function Increases Drp1-dependent Mitochondrial Fragmentation
A. Kathrin Lutz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
α-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex I activity
Guangwei Liu et al.
NEUROSCIENCE LETTERS (2009)
Silencing of PINK1 Expression Affects Mitochondrial DNA and Oxidative Phosphorylation in DOPAMINERGIC Cells
Matthew E. Gegg et al.
PLOS ONE (2009)
Mitochondrial Alterations in PINK1 Deficient Cells Are Influenced by Calcineurin-Dependent Dephosphorylation of Dynamin-Related Protein 1
Anna Sandebring et al.
PLOS ONE (2009)
Mitochondrial dysfunction in the striatum of aged chronic mouse model of Parkinson's disease
Gaurav Patki et al.
FRONTIERS IN AGING NEUROSCIENCE (2009)
Genetic factors involved in the pathogenesis of Parkinson's disease
Frank J. S. Lee et al.
BRAIN RESEARCH REVIEWS (2008)
Mitochondrial association of alpha-synuclein causes oxidative stress
M. S. Parihar et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Mitochondrial import and accumulation of α-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain
Latha Devi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Mitochondrial alterations in Parkinson's disease: new clues
Miquel Vila et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Mitochondria in the aetiology and pathogenesis of Parkinson's disease
Anthony H. V. Schapira
LANCET NEUROLOGY (2008)
Superoxide dismutase overexpression protects dopaminergic neurons in a Drosophila model of Parkinson's disease
Jose A. Botella et al.
NEUROBIOLOGY OF DISEASE (2008)
Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells
Shaik Shavali et al.
NEUROSCIENCE LETTERS (2008)
C-elegans model identifies genetic modifiers of α-synuclein inclusion formation during aging
Tjakko J. van Ham et al.
PLOS GENETICS (2008)
Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster
Jian Chen et al.
GENOME RESEARCH (2008)
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin
Nicole Exner et al.
JOURNAL OF NEUROSCIENCE (2007)
Tumor necrosis factor-associated protein 1 (TRAP-1) protects cells from oxidative stress and apoptosis
N. Montesano Gesualdi et al.
STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS (2007)
Localization of α-synuclein to mitochondria within midbrain of mice
Wen-Wei Li et al.
NEUROREPORT (2007)
Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis
Guoqiang Hua et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
Julia W. Pridgeon et al.
PLOS BIOLOGY (2007)
Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication
J. Fuchs et al.
NEUROLOGY (2007)
Relationships between the sequence of α-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity
Michael J. Volles et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain
Andisheh Eslamboli et al.
BRAIN (2007)
Pesticide exposure exacerbates α-synucleinopathy in an A53T transgenic mouse model
Erin H. Norris et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Iron chelation study in a normal human hepatocyte cell line suggests that tumor necrosis factor receptor-associated protein 1 (TRAP1) regulates production of reactive oxygen species
Chang-Nim Im et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Understanding the molecular causes of Parkinson's disease
A. Wood-Kaczmar et al.
TRENDS IN MOLECULAR MEDICINE (2006)
Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled
Paula M. Keeney et al.
JOURNAL OF NEUROSCIENCE (2006)
Expanding insights of mitochondrial dysfunction in Parkinson's disease
PM Abou-Sleiman et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Parkinson's disease α-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death
LJ Martin et al.
JOURNAL OF NEUROSCIENCE (2006)
Early signs of neuronal apoptosis in the substantia nigra pars compacta of the progressive neurodegenerative mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model of Parkinson's disease
L. Novikova et al.
NEUROSCIENCE (2006)
Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity
WW Smith et al.
HUMAN MOLECULAR GENETICS (2005)
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease
KM Strauss et al.
HUMAN MOLECULAR GENETICS (2005)
Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP
DD Song et al.
EXPERIMENTAL NEUROLOGY (2004)
Comparison of kindreds with parkinsonism and α-synuclein genomic multiplications
M Farrer et al.
ANNALS OF NEUROLOGY (2004)
α-synuclein locus duplication as a cause of familial Parkinson's disease
MC Chartier-Harlin et al.
LANCET (2004)
PINK1 mutations are associated with sporadic early-onset parkinsonism
EM Valente et al.
ANNALS OF NEUROLOGY (2004)
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
AM Cuervo et al.
SCIENCE (2004)
Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by β-hydroxyisovalerylshikonin
Y Masuda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8-and-9-mediated apoptotic pathways in dopaminergic neurons
WS Choi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
α-synuclein locus triplication causes Parkinson's disease
AB Singleton et al.
SCIENCE (2003)
Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human α-synuclein
M Lakso et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Aggregated and monomeric α-synuclein bind to the S6′ proteasomal protein and inhibit proteasomal function
H Snyder et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Phosphorylation of α-synuclein characteristic of synucleinopathy lesions is recapitulated in α-synuclein transgenic Drosophila
M Takahashi et al.
NEUROSCIENCE LETTERS (2003)
Parkin protects against the toxicity associated with mutant α-synuclein:: Proteasome dysfunction selectively affects catecholaminergic neurons
L Petrucelli et al.
NEURON (2002)
α-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease
C Lo Bianco et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease
PK Auluck et al.
SCIENCE (2002)
Modelling neurodegenerative diseases in Drosophila: a fruitful approach?
MMK Muqit et al.
NATURE REVIEWS NEUROSCIENCE (2002)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
Inducible expression of mutant α-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
Y Tanaka et al.
HUMAN MOLECULAR GENETICS (2001)
α-synuclein promotes mitochondrial deficit and oxidative stress
LJ Hsu et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
A Drosophila model of Parkinson's disease
MB Feany et al.
NATURE (2000)
Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease:: Implications for pathogenesis and therapy
KA Conway et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Share Paper
